Results 161 to 170 of about 4,371,683 (305)

Pathogenic Role of FGFR3 Autoantibodies in Small Fiber Neuropathy

Advanced Science, EarlyView.
Autoantibodies against fibroblast growth factor receptor 3 (FGFR3) are identified as pathogenic drivers of pain in small fiber neuropathy. By binding to sensory neurons in dorsal root ganglia, FGFR3 autoantibodies activate MAPK signaling and induce hyperexcitability and mechanical hypersensitivity, establishing FGFR3 autoantibodies as a therapeutic ...
Lyuba Y. Salih, Nicolas L.A. Dumaire, Clémence Gieré, Erin Vest, Haya Alkhateeb, Christian P. Moritz, Yannick Tholance, Jean‐Philippe Camdessanché, Jean‐Christophe Antoine, Jérôme Honnorat, Jafar Kafaie, Liberty François‐Moutal, Aubin Moutal   +12 more
wiley   +1 more source

J.H.J. van den Heuvel, Een vrij zinnige verhouding. De VPRO en Nederland 1926-1986

BMGN: Low Countries Historical Review, 1988
J.Th.M. Bank
doaj   +1 more source

Transcriptomic response to <i>Borrelia afzelii</i> infection in the skin of wild bank voles. [PDF]

Microbiol Spectr
Różańska-Wróbel J, Konczal M, Notarnicola RF, Radwan J.   +3 more
europepmc   +1 more source

Cleavage‐Resistant CYLD Protects Against Autoimmune Hepatitis

Advanced Science, EarlyView.
Proteolytic cleavage of the deubiquitinase CYLD emerges as a critical driver of autoimmune hepatitis. TNFα‐induced CYLD loss in macrophages amplifies S100A9‐triggered MAPK activation, leading to excessive chemokine production and hepatic inflammation. Pharmacological inhibition of MEK signaling effectively attenuates experimental disease, highlighting ...
Han Liu, Chen Su, Jianling Liu, Mingyan Xing, Xiaoxia Wu, Lingxia Wang, Xiaoming Zhao, Hanwen Zhang, YangYang Xie, YangYang Wang, Hong Li, Yu Li, Ming Li, Haibing Zhang   +13 more
wiley   +1 more source

A Weibull distribution-based method for estimating seed longevity in <i>Solanum rostratum</i>. [PDF]

Front Plant Sci
Yuan Z, Fu W, Song Z, Wang Z, Sun C, Zhang Y, Zhang G.   +6 more
europepmc   +1 more source

ITGB1 Regulates Triple‐Negative Breast Cancer Development by Modulating the Tumor Microenvironment

Advanced Science, EarlyView.
ABSTRACT Tumorigenesis and metastasis are frequently attributed to the intricate interplay between cancer cells and the tumor microenvironment (TME). Comprehending the mechanisms and key regulators of cancer‐immune crosstalk in the TME is imperative for developing efficacious immunotherapy.
Nuozi Song, Siqi Chen, Lei Wang, Jessica Dang, Xu Cao, Stephanie Singh, Lu Yang, Jinhui Wang, Steven T. Rosen, Yingyu Wang, Chun‐Wei D. Chen, Cheng Zhang, Mingye Feng   +12 more
wiley   +1 more source

Regional financial integration in Asia: present and future [PDF]

Bank for International Settlements, Bank for International Settlements   +1 more
core   +6 more sources

P. Luykx, De actie 'voor God' 1936-1941. Een katholieke elite in het offensief

BMGN: Low Countries Historical Review, 1979
J.Th.M. Bank
doaj   +1 more source

Correction for Szewczyk et al., Liganded LolCDE structures reveal a common substrate-LolE interaction guiding bacterial lipoprotein transport. [PDF]

Proc Natl Acad Sci U S A
europepmc   +1 more source

An Australian brain bank and the future of alcohol and major neuropsychiatric disorders research. [PDF]

Front Neurol
Stevens J, Smith CC, Maskey D, Novelli M, Bronfenbrener J, Hofer MJ, Sutherland GT.   +6 more
europepmc   +1 more source