Results 231 to 240 of about 2,064,544 (318)

Leaf-Specific Classification of Multi-Leaf Collimator Positioning Errors in Volumetric Modulated Arc Therapy Using a Convolutional Neural Network. [PDF]

J Clin Med
Shin JY, Choi CH, Kim JI, Park JM, Cheon W, Park SY.   +5 more
europepmc   +1 more source

O‐GlcNAcylation Regulation of SNAP29‐Dependent Autophagy Activation Dictates Chemoresistance in Gastric Cancer

Advanced Science, EarlyView.
Model illustrating the proposed mechanism by which chemotherapy‐induced downregulation of OGT disrupts SNAP29 O‐GlcNAcylation, promoting STX17‐SNAP29‐VAMP8 SNARE complex assembly and protective autophagy, leading to chemoresistance, which in turn establishes a feedforward loop to perpetuate drug tolerance.
Liang Tang, Shaoji Zhao, Ziling Shao, Tao Luo, Baifu Peng, Yifan Liu, Jinning Ye, Jianjun Peng, Kaiyu Sun, Jianbo Xu   +9 more
wiley   +1 more source

Measuring satisfaction with orthotic and prosthetic devices. [PDF]

Qual Life Res
Tyner CE, Boulton AJ, Slotkin J, Kisala PA, Zafonte R, Childers WL, Dearth CL, Butkus J, Tulsky DS.   +8 more
europepmc   +1 more source

Integrated Single‐Cell and TCR Profiling Reveals Protection‐Associated CD8+ T Cell Subsets Linked to Viral Control in PRRSV

Advanced Science, EarlyView.
PRRSV vaccine‐mediated protection is associated with clonally expanded cytotoxic CD8+ T cell subsets driven by viral structural proteins and supported by innate TLR4/TLR8 signaling and CD4+ T cell help, whereas non‐protective responses are characterized by dysfunctional exhausted‐like CD8+ T cells linked to poor viral control.
Can Kong, Siang Chen, Maolin Li, Meng Wang, Hailin Zhang, Bolun Zhou, Zhenhua Xie, Chen Wang, Peng Gao, Jianjun Luo, Hanchun Yang, Runsheng Chen, Dongdong Zhang, Jie Li, Jun Han   +14 more
wiley   +1 more source

Designing a provider-led multimorbidity care model for fragmented insurance-based health systems: A mixed-methods study in Colombia. [PDF]

PLoS One
Valencia O, Bernal O.
europepmc   +1 more source

Ole Jensens erindringer er historien om, hvordan en teologisk grundholdning bliver til

Fønix, 2020
Anna Bank Jeppesen
doaj  

Wake‐Up and Fatigue under Electrical Cycling in HfO2‐Based Ferroelectrics: Mechanisms and Strategies toward Reliable Devices

Advanced Science, EarlyView.
HfO2‐based ferroelectrics exhibit wake‐up and fatigue behaviors during electrical cycling, significantly affecting device endurance and reliability. These phenomena are governed by defect dynamics, including oxygen vacancy redistribution and charge trapping.
Hongseok Kim, Shinhyeong Lee, Hyojun Choi, Minseung Park, Hyunah Cho, Min Hyuk Park, Yunseok Kim   +6 more
wiley   +1 more source

Evidence of a Potential Nursery Area for the Great Hammerhead Shark, <i>Sphyrna mokarran</i>, in the Largest Coral Reef System of the Southwestern Atlantic. [PDF]

Ecol Evol
Santander-Neto J, Barreto R, Lírio GDS, Heithaus M, Gadig OBF, Hostim-Silva M.   +5 more
europepmc   +1 more source

Ahcy Acts as an Effector of Hnf4a‐Driven Super‐Enhancer Activation to Alleviate MASLD During Intermittent Fasting

Advanced Science, EarlyView.
Our study identifies an Hnf4a‐driven super‐enhancer of hepatic Ahcy that mediates the protective effects of intermittent fasting against MASLD. Disruption of the Ahcy super‐enhancer reduces Ahcy expression and exacerbates lipid accumulation. This pathway prevents aberrant promoter hypermethylation by maintaining the SAM/SAH balance, as exemplified by ...
Huafeng Chen, Shilin Zhang, Xiaojie Deng, Wenqiang Xie, Fen Xu, Jie Shen, Hua Liang   +6 more
wiley   +1 more source

Factors Associated with Endothelial Cell Density at One Year in the Diabetes Endothelial Keratoplasty Study. [PDF]

Ophthalmology
Patel SV, Benetz BA, Price MO, Reed ZW, Gal RL, Szczotka-Flynn LB, Ayres BD, Boyce M, Croasdale CR, Hamill MB, Hansen MS, Omar AF, Potts LB, Vislisel JM, Beck RW, Lass JH, Diabetes Endothelial Keratoplasty Study Group.   +16 more
europepmc   +1 more source