Results 151 to 160 of about 1,679,935 (308)
Advanced Science, EarlyView.This work designed an injectable metal‐drug supramolecular condensate formed from hafnium ions and alendronate (Hf‐ALN) and loaded with the COX‐2 inhibitor celecoxib (CXB) for synergistic radioimmunotherapy of postoperative osteosarcoma. Mechanistically, upon X‐ray irradiation, Hf enhances radiation energy deposition, ROS generation, and DNA damage ...
Tianhua Xiao +12 more
wiley +1 more source
Liquidity, Contagion and Financial Crisis [PDF]
We develop a theoretical model where a redistribution of bank capital (e.g., due to reckless trading and/or faulty risk management) leads to a “freeze” of the interbank market. The fire-sale market plays a central role in spreading the crisis to the real
Guembel, Alexander, Sussman, Oren
core
Advanced Science, EarlyView.A new class of lysosome‐directed molecular glue degraders selectively enhance CAPRIN1–APP interactions, driving APP degradation and reducing amyloid‐β production in human neurons and Alzheimer's disease mouse models. This CAPRIN1‐dependent targeted protein degradation strategy reveals a previously unrecognized therapeutic approach for disrupting the ...
Sunghan Jung +15 more
wiley +1 more source
Liquidity, Efficiency and Bank Bailouts [PDF]
Why do governments bailout banking systems in distress? We argue that the government can efficiently provide liquidity. We present a general equilibrium model in which not all assets can be used to purchase all other assets at every date.
Gary Gorton, Lixin Huang
core
Intelligent Programmable Membrane Nanosponge for Early Virus Blocking
Advanced Science, EarlyView.A smart programmable nanosponge (ACNPs) displays high‐density viral receptors on its membrane and encapsulates fusion inhibitors to capture virions at the infection source through competitive binding and blocks their entry through protease inhibition for ultra‐early cascade interception. This modular, mucus‐penetrating platform shifts antiviral defence
Ze Chen +17 more
wiley +1 more source
Issuing central bank securities [PDF]
Many central banks around the world are faced with the challenge of implementing their policy goals in the presence of surplus liquidity in domestic banking systems.
Garreth Rule
core
Advanced Science, EarlyView.This study characterizes MfAgo, an enzyme exhibiting highly efficient DNA‐guided DNA and RNA cleavage capability. Precise RNA cleavage strictly requires dimerization to stabilize the PIWI‐loop region, while its robust DNA cleavage functions in a dimerization‐independent manner.
Fuyong Huang +9 more
wiley +1 more source
THE DECISION OF MANAGING BANKS’ LIQUIDITY RISK IN MACEDONIA
Iustinianus Primus Law Review, 2011 The main purpose of this paper is to analyze Macedonian lawframework for providing liquidity of a bank. At the end of the year 2003, the National Bank of the Republic of Macedonia (NBRM) has adopt adequate regulation in order to provide the basic ...
Biljana Petrevska
doaj
Bank of Finland. Bulletin [PDF]
, 2004 Monetary policy and economic outlook 1 Tapio Korhonen Risks related to increasing debt and ample liquidity 14 Tuuli Koivu Will rapid growth in China continue?
core
Advanced Science, EarlyView.We use lysine‐to‐glutamine mutations to study the effect of electrostatics on the kinetics and thermodynamics of alpha‐synuclein amyloid fibril formation. We find that mutational effects map on their structural context within fibrils and identify residues that modulate the energy landscape of alpha‐synuclein self‐assembly. Our work outlines a scalable,
Antonin Kunka +10 more
wiley +1 more source