Results 1 to 10 of about 6,550 (226)

Galacto-Oligosaccharide RP-G28 Improves Multiple Clinical Outcomes in Lactose-Intolerant Patients [PDF]

Nutrients, 2020
Background and Aims: Lactose intolerance (LI) is a global problem affecting more than half of the world’s population. An ultra-purified, high-concentration galacto-oligosaccharide, RP-G28, is being developed as a treatment for patients with LI. The efficacy and safety of RP-G28 in reducing symptoms of lactose intolerance were assessed in a blinded ...
William Chey, William Sandborn, Andrew J. Ritter, Howard Foyt, M. Andrea Azcarate-Peril, Dennis A. Savaiano   +5 more
openaire   +3 more sources

EGCG-Derivative G28 Shows High Efficacy Inhibiting the Mammosphere-Forming Capacity of Sensitive and Resistant TNBC Models [PDF]

Molecules, 2019
Recent studies showed that Fatty Acid Synthase (FASN), a lipogenic enzyme overexpressed in several carcinomas, plays an important role in drug resistance. Furthermore, the enrichment of Breast Cancer Stem Cell (BCSC) features has been found in breast tumors that progressed after chemotherapy. Hence, we used the triple negative breast cancer (TNBC) cell
Ariadna Giró-Perafita, Marc Rabionet, Marta Planas, Lidia Feliu, Joaquim Ciurana, Santiago Ruiz-Martínez, Teresa Puig   +6 more
core   +6 more sources

Fatty Acid Synthase Inhibitor G28 Shows Anticancer Activity in EGFR Tyrosine Kinase Inhibitor Resistant Lung Adenocarcinoma Models [PDF]

Cancers, 2020
Epidermal growth factor receptor (EGFR) tyrosine kinases inhibitors (TKIs) are effective therapies for non-small cell lung cancer (NSCLC) patients whose tumors harbor an EGFR activating mutation. However, this treatment is not curative due to primary and secondary resistance such as T790M mutation in exon 20.
Emma Polonio-Alcalá, Sònia Palomeras, Daniel Torres-Oteros, Joana Relat, Marta Planas, Lidia Feliu, Joaquim Ciurana, Santiago Ruiz-Martínez, Teresa Puig   +8 more
openaire   +6 more sources

Gynaecology Teaching Associates in Medical Education-A Scoping Review. [PDF]

Clin Teach
ABSTRACT Background Pelvic examination is a core, yet anxiety‐provoking, clinical skill in undergraduate medical education. Traditional teaching approaches—often opportunistic or reliant on simulation—have been criticised for disembodying technical skill from relational and ethical practice. Gynaecology Teaching Associates (GTAs), trained educators who
Kelly C, Bell E, Brown MEL, Stelling H.
europepmc   +2 more sources

Ganymede: very high resolution data from G28 reveal new perspectives on processes and history

, 2001
Recent G28 very high resolution image data provides new insight into five major problem areas and shows evidence for strike-slip faulting and processes perhaps like Europa band ...
Head, J.W., Pappalardo. R.,, Collins, G.C. (Dept. Geol. Sci., Brown Univ., Providence, RI, USA),, Spaun, N.A., Nixon, B., Wagner, R., Giese, B., Neukum, G.   +7 more
openaire   +2 more sources

Integrative genomics and regulomics reveal the molecular architecture of complex traits in domestic chickens. [PDF]

Imeta
Domestic chickens (Gallus gallus domesticus) exhibit exceptional phenotypic diversity and provide a valuable model for studying domestication and artificial selection. We integrated whole‐genome resequencing data from ~3000 individuals with 20 slaughter‐related traits.
Han W, Zhou C, You Y, Li G, Zhu Y, Tang Y, Zeng T, Zhang H, Xue Q, Yin J, Chen L, Ju X, Jiang Y, Cai J, Li L, Zhang X, Lin Z, Ren J, Lu L, Chen D.   +19 more
europepmc   +2 more sources

Characterization of 2S albumin allergenic proteins for anaphylaxis in common buckwheat

Food Chemistry: Molecular Sciences, 2022
2S albumin (2SA) is responsible for anaphylaxis following consumption of buckwheat in allergic individuals. To reduce allergen incidents, characterization of 2SA polypeptides is prerequisite, thus was analyzed in this study. Of the five 2S albumin genes (
Tomoyuki Katsube-Tanaka, Fakhrul Islam Monshi   +1 more
doaj   +1 more source

The Impact of Macroprudential Policy on Credit Growth in Nine Euro Area Economies

Naše Gospodarstvo, 2023
In this paper, we investigate the impact of macroprudential policy measures (bundled together into a macroprudential policy index, MPI) on the non-financial corporate sector credit and household credit growth using a one-step system GMM empirical ...
Lorenčič Eva, Volčjak Robert, Festić Mejra   +2 more
doaj   +1 more source

Empirical Analysis of Financial Development and Financial Inclusion Nexus in Nigeria

Studia Ekonomiczne i Regionalne, 2022
Subject and purpose of work: The literature on financial development and economic growth is expansive. The proportion of individuals and firms that use or have access to financial services can be referred to as the financially included.
Anthony-Orji Onyinye I., Orji Anthony, Ogbuabor Jonathan E., Onwe Israel Emenike   +3 more
doaj   +1 more source

Market Structure Development in a Regulated Market: The Case of the EU Rating Agencies

Business Systems Research, 2021
Background: The motivation for this article is the observation of political and private efforts to establish an EU-based rating agency as a counterweight to the three major agencies and observe other approaches to increase competition in the rating ...
Meeh-Bunse Gunther, Schomaker Stefan
doaj   +1 more source