Results 61 to 70 of about 242,121 (318)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Inter-American Development Bank Sustainability Report 2013

open access: yes, 2014
This Sustainability Report details sustainability progress and performance of the IDB against our commitments throughout the 2013 fiscal year. The report details our progress on investing in and safeguarding sustainability through our project portfolio ...
Inter-American Development Bank
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Scale Factor in the Performance of Deposit Banks – The Turkey Case

open access: yesEkonomi, Politika & Finans Araştırmaları Dergisi, 2023
The objective of this research was to clarify how the scale factor and bank performance relate to one another. It was observed that the benefit of scale emerged in various economic areas.
Şenol Babuşcu   +2 more
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

PENGARUH KINERJA KEUANGAN DAN KONDISI MAKROEKONOMI TERHADAP PEMBIAYAAN BERMASALAH BPR SYARIAH DI INDONESIA

open access: yesEquilibrium: Jurnal Ekonomi Syariah, 2019
This study is to evaluate the bank performances and macroeconomic conditions to the NPF. Internal factors consist of Capital Adequacy Ratio (CAR), Financing to Deposits Ratio (FDR), Return on Assets (ROA), operating income operating expenses (BOPO ...
Ahmad Fatoni, Kurnia Dwi Sari Utami
doaj   +1 more source

The Influence of Self-Efficacy and Islamic Financial Literacy on the Performance of Micro, Small, and Medium-Sized Enterprises

open access: yesEconomica: Jurnal Ekonomi Islam, 2021
MSMEs have long promoted a major contribution to the national economy. However, the Covid-19 pandemic has caused MSME to suffer a decline resulting in a direct effect on the economy in Indonesia.
Popon Srisusilawati   +5 more
doaj   +1 more source

Ramifications of varying banking regulations on performance of Islamic Banks [PDF]

open access: yesBorsa Istanbul Review, 2019
Recent financial crises have highlighted the importance of banking regulations to hedge against the high risk accredited to imbalances in banks' balance sheets. Nonetheless, banking regulations may have adverse effects. On the one hand, they serve as prudential measures that alleviate the effects of crises on the stability of the banking system while ...
Nafis Alam   +2 more
openaire   +2 more sources

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Home - About - Disclaimer - Privacy