Results 81 to 90 of about 242,121 (318)
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Inter-American Development Bank Quarterly Business Review: First Quarter 2011
, 2011 The 2011 first quarter edition of the Quarterly Business Review (QBR) provides management with a status of the Bank\u27s performance. The QBR reports on outputs, lending program priorities and organizational indicators on a quarterly basis to allow ...
Inter-American Development Bank
core +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Performance Evaluation of the Taiwanese Banking Industry before and after the COVID-19 Pandemic
MathematicsThis study aimed to explore efficiency changes in Taiwan’s banking industry before and after the outbreak of coronavirus disease 2019 (COVID-19) by using the maximum slacks-based measure approach.
Chuan-Feng Lee, Fu-Chiang Yang
doaj +1 more source
Inter-American Development Bank Quarterly Business Review: Third Quarter 2011
, 2011 The 2011 third quarter edition of the Quarterly Business Review (QBR) provides management with a status of the Bank\u27s performance. The QBR reports on outputs, lending program priorities and organizational indicators on a quarterly basis to allow ...
Inter-American Development Bank
core +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Governance and Performance of Tunisian Banks [PDF]
International Journal of Economics and Finance, 2010 Developing banking standards is an important process for a country’s financial and economic well being. Their importance incites governments to insure the stability and the performance of their banking systems. Accordingly, several researchers pay a particular attention to banking governance.
openaire +2 more sources
Inter-American Development Bank Annual Business Review 2015
, 2016 The 2015 Annual Business Review (ABR) provides management with a status of the Bank\u27s performance. The ABR reports on outputs, lending program priorities, and organizational indicators on a yearly basis to allow management to monitor progress in ...
Inter-American Development Bank
core +1 more source
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Determinants of Bank Performance in a Developing Country: Evidence From Morocco
Organizations and Markets in Emerging Economies, 2017 This paper aims to define long-term determinants of Moroccan commercial banks performance, for the period 2005-2015, using the Johansen cointegration test.
El Mehdi Ferrouhi
doaj +1 more source