Results 241 to 250 of about 1,081,363 (314)

T-cadherin deprivation in endothelial cells promotes vascular injury in Kawasaki disease through SOD2/ROS/NLRP3 pathway-mediated pyroptosis. [PDF]

J Mol Cell Biol
Lin Y, Wang F, Luo X, Yang X, Yang W, Lu Z, Wang Z, Zhou H, Ruan M, Chen K, Fu L, Pi L, Che D, Yu H, Gu X.   +14 more
europepmc   +1 more source

Coronavirus Nsp3 Hijacks CLTC to Modulate Autophagosome Nucleation for Promoting DMV Formation and Viral Replication

Advanced Science, EarlyView.
In wild‐type cells, FIPV infection recruits CLTC to nsp3, facilitates DMV biogenesis and block autophagic flux to promote viral replication. CLTC knockout impairs autophagosome nucleation by reducing Beclin1–ATG14 complex expression. This disrupts the formation of autophagic precursor membranes, thereby preventing their hijacking by nsp3 for DMV ...
Juan Xu, Hang Li, Peng Liu, Zhe Jiao, Ding Zhang, Zhelin Su, Sai Niu, Jintao Zhang, Yuejun Shi, Guiqing Peng   +9 more
wiley   +1 more source

Cell bank system, establishment, and application in the virus research, diagnosis, and biopharmaceutical industries. [PDF]

Biotechnol Notes
Soleimani S, Ghorani M.
europepmc   +1 more source

Loss of VMP1 Impairs Tight Junction Recycling and Aggravates Intestinal Barrier Dysfunction in Inflammatory Bowel Disease

Advanced Science, EarlyView.
This study identifies vacuole membrane protein 1 (VMP1) as a critical regulator of intestinal epithelial barrier homeostasis. VMP1 facilitates the recruitment of CORO1C to late endosomes, supporting Retromer‐mediated recycling of the tight junction protein Occludin.
Jiawei Zhao, Jianjun Zou, Chen Zhou, Yingui Wang, Yiman Liu, Yanqing Zhou, Yuxiang Wang, Xinyu Zhang, Huishu Yang, Hongjie Yin, Dongsheng Bai, Yue Zhao, Na Lu   +12 more
wiley   +1 more source

The China Brain Multi-omics Atlas Project (CBMAP). [PDF]

Mol Psychiatry
Zhou D, Zhou Y, Sun Z, Ji F, Zhang D, Wang Q, Ruan Y, Wang Y, Zhu Y, Sun X, Li MJ, Yuan C, Liu K, Sun L, Zhai W, Fan J, Zhu K, Qiu W, Yan X, Ma C, Shen Y, Bao A, Yue W, Shi Y, Chen C, Yang J, Duan S, Zhang J, CBMAP Consortium.   +28 more
europepmc   +1 more source

Artesunate Ameliorates APAP‐induced Liver Injury by Promoting NEDD4L‐Mediated Ubiquitination and Degradation of TXNIP

Advanced Science, EarlyView.
ABSTRACT Liver injury can lead to severe acute liver failure and even death in patients. Artesunate (ART), which is a derivative of artemisinin that has been approved by the FDA for the treatment of malaria, has significant regulatory effects on cell death and inflammation.
Zhe Zhang, Hongyi Zhang, Haixiang Guo, Xiwen Zhang, Yidan Wang, Baoyin Wang, Tong Wang, Guokun Zhao, Qing Zhang, Fei Gao, Shuang Liang, Hao Jiang, Yu Ding, Xiliang Du, Jiabao Zhang, Yi Zheng, Xinwei Li, Bao Yuan   +17 more
wiley   +1 more source

The Mediating Role of Emotion Dysregulation in the Association Between Impulsivity and Severity of Substance Dependence. [PDF]

Clin Psychol Psychother
Mansueto G, Palmieri S, Nikčević AV, Caselli G, Spada MM.   +4 more
europepmc   +1 more source

BZW1 Drives Immune Evasion in Lung Adenocarcinoma via Ferroptosis Suppression

Advanced Science, EarlyView.
BZW1 attenuates ferroptosis by competitively binding NCOA4 and suppress ferrtinophagy‐mediated iron release. The depletion of BZW1 triggers lipid peroxidation through iron homeostasis. Extracellularly, BZW1 attenuates immunogenic cell death and reinvigorates cytotoxic T‐cell responses.
Linyao Zhao, Yue Peng, Qing Liang, Shi Liu, Yang Li, Lei Ma, Menghan Hu, Sujuan Zheng, Zhihua Liu, Shugeng Gao   +9 more
wiley   +1 more source

The impact of data protection laws on Chinese digital cross-border mergers and acquisitions: A quasi-natural experiment based on the EU's general data protection regulation. [PDF]

PLoS One
Yu M, Ye X.
europepmc   +1 more source