Results 51 to 60 of about 1,081,363 (314)

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

open access: yesMolecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli   +7 more
wiley   +1 more source

International competition in bank regulation

open access: yesPSL Quarterly Review, 2013
The work identifies current and future changes in the international banking system, and considers the effect of these changes on regulation and on banking stability.
I. GIDDY, D. ALLEN
doaj   +1 more source

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

open access: yesFEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima   +4 more
wiley   +1 more source

MONETARY POLICY FORCE EFFECT BY MEANS OF BANKS MONEY CREATION [PDF]

open access: yesFinancial Studies, 2014
In the context of modern economy, banks play an essential role for sustainable growth, by ensuring economy with financial resources and driving impulses of monetary policy to economy.
Victoria COCIUG, Olga TIMOFEI
doaj  

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

open access: yesFEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli   +9 more
wiley   +1 more source

Differential lncRNA expression in the ovarian tissue of Wanxi white goose at different laying stages and the its mechanism of egg laying

open access: yesPoultry Science
A transcriptome sequencing analysis on ovarian tissues of Wanxi white geese (WWG) at different laying periods (pre-laying, laying, and eased) explored the effects of lncRNA, miRNA, and mRNA on the follicular development and egg production performance of ...
Yuhua Wang   +8 more
doaj   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

open access: yesFEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold   +11 more
wiley   +1 more source

Croatian banks profitability under capital requirements pressure

open access: yesManagement : Journal of Contemporary Management Issues, 2021
Regulating bank behavior throughout capital requirements has been a focal point of prudential regulation since the late 1980s. However, their beneficial effect on the banking sector's safety and soundness was disputed ever since their initial ...
Ana Kundid Novokmet, Ana Pavić
doaj  

Capital regulation and bank lending [PDF]

open access: yes
Bank regulation in general and capital regulation in particular are widely perceived as having become stiffer in the 1990s. The stiffer regulatory environment in turn is argued to have curtailed bank lending.
Frederick T. Furlong
core  

The Need for Government and Central Bank Intervention in Financial Regulation: Free Banking and the Challenges of Information Uncertainty. [PDF]

open access: yes, 2012
Through a focus on the ever increasing need to address information asymmetries, as well as reference to the uniqueness of the degree to which systemic risks are triggered in banking, this paper aims primarily to highlight reasons why government and ...
Ojo, Mariane.B.
core  

Home - About - Disclaimer - Privacy