Results 251 to 260 of about 5,690,370 (308)

A Comparison of Item Selection Methods and Parameter Estimation Approaches for Online Calibration in Computerized Adaptive Testing. [PDF]

Educ Psychol Meas
Ertuna L, Glas CAW, Atar B.
europepmc   +1 more source

Targeting LDHA Palmitoylation Sensitizes GBM to Chemoradiotherapy via Suppressing Palmitic Acid Induced Glycolytic Reprogramming

Advanced Science, EarlyView.
Mesenchymal GSCs preferentially uptake palmitic acid, thereby promoting ZDHHC12‐mediated LDHA palmitoylation. This modification enhances LDHA enzymatic activity, drives glycolytic reprogramming, and facilitates exosomal LDHA‐mediated TAM regulation.
Zijie Gao, Rongrong Zhao, Zheyuan Chen, Qingtong Wang, Huanyu Yang, Boyan Li, Yanhua Qi, Shulin Zhao, Jixing Zhao, Jiawei Qiu, Ziwen Pan, Zhe Han, Ruochuan Li, Huize Xia, Weijie Tang, Xing Guo, Ping Zhang, Hongyu Zhao, Xu Qian, Gang Li, Hao Xue   +20 more
wiley   +1 more source

Dietary transition proxies and ischemic heart disease burden: a country-year panel analysis with a systematic robustness assessment. [PDF]

Front Nutr
Oh MY.
europepmc   +1 more source

An Injectable Metal‐Drug Supramolecular Condensate Enables Radiosensitization and Systemic Antitumor Immunity for Post‐Surgical Osteosarcoma Therapy

Advanced Science, EarlyView.
This work designed an injectable metal‐drug supramolecular condensate formed from hafnium ions and alendronate (Hf‐ALN) and loaded with the COX‐2 inhibitor celecoxib (CXB) for synergistic radioimmunotherapy of postoperative osteosarcoma. Mechanistically, upon X‐ray irradiation, Hf enhances radiation energy deposition, ROS generation, and DNA damage ...
Tianhua Xiao, Zunlei Gong, Chuke Chen, Hui Yu, Yu Cai, Can Liu, Hongkai Huang, Ying Li, Jinyuan Guan, Le Wang, Chengyun Ning, Guoxin Tan, Lei Zhou   +12 more
wiley   +1 more source

Fenced enclosure and increased rainfall facilitate recovery of degraded desert steppe by restructuring soil seed bank dynamics. [PDF]

BMC Plant Biol
Chen H, Fan G, Baskin CC, Baskin JM, Cui Q, Liu H, Huang Z.   +6 more
europepmc   +1 more source

Molecular Glue Degraders Enhance CAPRIN1‐Dependent Lysosomal Degradation of APP and Reduce Amyloid β in Alzheimer's Disease

Advanced Science, EarlyView.
A new class of lysosome‐directed molecular glue degraders selectively enhance CAPRIN1–APP interactions, driving APP degradation and reducing amyloid‐β production in human neurons and Alzheimer's disease mouse models. This CAPRIN1‐dependent targeted protein degradation strategy reveals a previously unrecognized therapeutic approach for disrupting the ...
Sunghan Jung, Xu Wang, Bin Liu, Raktim Roy, Nancy Jaiswal, Ratan K. Rai, Yuichiro Takagi, Cen Gao, Lifan Zeng, Ho‐Yin Lo, Reagan K. Wohlford, Ryan K. Higgins, Bruce T. Lamb, Anantha Shekhar, Anita C. Bellail, Chunhai Hao   +15 more
wiley   +1 more source

Fertility Preservation in Female Patients with Cancer. Part III: Royan Human Ovarian Tissue Bank Guideline for Prepubertal Girls and Women, A Review. [PDF]

Int J Fertil Steril
Abtahi NS, Ghezelayagh Z, Fathi R, Rezazadeh Valojerdi M, Ebrahimi B.   +4 more
europepmc   +1 more source

Relationship between age, pseudophakia, diabetes mellitus and endothelial cell density in corneal donor tissue: a 10-year retrospective study. [PDF]

BMJ Open Ophthalmol
Shavit I, Salminis Linzen S, Shvaiger A, Tiosano A, Livny E, Dotan A.   +5 more
europepmc   +1 more source

Green Banking and Bank Performance in ASEAN: The Moderating Role of Bank Size

Journal of Logistics, Informatics and Service Science
openaire   +1 more source

Co-Circulation of Divergent Strains Supports Vector-Mediated Transmission of Rodent Hepacivirus J (<i>Orthohepacivirus glareoli</i>). [PDF]

Viruses
Marmorosch S, von Graffenried TA, Ulrich RG, Heckel G.   +3 more
europepmc   +1 more source