Results 181 to 190 of about 28,143 (215)

The Role of Sleep Banking in Reducing Cognitive and Motor Impairments from Subsequent Sleep Restriction: A Narrative Review. [PDF]

Clocks Sleep
Juginović A, Rodman L.
europepmc   +1 more source

Molecular Glue Degraders Enhance CAPRIN1‐Dependent Lysosomal Degradation of APP and Reduce Amyloid β in Alzheimer's Disease

Advanced Science, EarlyView.
A new class of lysosome‐directed molecular glue degraders selectively enhance CAPRIN1–APP interactions, driving APP degradation and reducing amyloid‐β production in human neurons and Alzheimer's disease mouse models. This CAPRIN1‐dependent targeted protein degradation strategy reveals a previously unrecognized therapeutic approach for disrupting the ...
Sunghan Jung, Xu Wang, Bin Liu, Raktim Roy, Nancy Jaiswal, Ratan K. Rai, Yuichiro Takagi, Cen Gao, Lifan Zeng, Ho‐Yin Lo, Reagan K. Wohlford, Ryan K. Higgins, Bruce T. Lamb, Anantha Shekhar, Anita C. Bellail, Chunhai Hao   +15 more
wiley   +1 more source

A Systematic Literature Review on Biometric Authentication in Mobile Banking. [PDF]

F1000Res
Naji Ali H, Salim Mahmood Al-Dabbagh S.
europepmc   +1 more source

Targeting the CRYAB/β‐Catenin Axis with an MMP‐9‐Responsive Hydrogel Disrupts CTC Clusters to Suppress Progression of Hepatocellular Carcinoma after Radiofrequency Ablation

Advanced Science, EarlyView.
The graphical abstract illustrates that sublethal thermal stress after iRFA upregulates the chaperone CRYAB in residual HCC cells, which stabilizes β‐catenin and drives a dual pathological program, including EMT and N2‐TAN polarization, thereby leading to heterotypic CTC cluster formation. The MMP‐9‐responsive hydrogel (XB@Gel) delivers XAV‐939 and BMS‐
Hui Chen, Danni Yang, Songying Pi, Yuhan Liu, Hongbin Huang, Feile Ye, Yuhong Lin, Zhongzhen Su, Yongquan Huang   +8 more
wiley   +1 more source

Seeds of change: trait shifts over time in wild plant populations revealed using <i>ex situ</i> Seeds of Success collections. [PDF]

AoB Plants
Shriver LC, Barga SC, Leger EA.
europepmc   +1 more source

Intelligent Programmable Membrane Nanosponge for Early Virus Blocking

Advanced Science, EarlyView.
A smart programmable nanosponge (ACNPs) displays high‐density viral receptors on its membrane and encapsulates fusion inhibitors to capture virions at the infection source through competitive binding and blocks their entry through protease inhibition for ultra‐early cascade interception. This modular, mucus‐penetrating platform shifts antiviral defence
Ze Chen, Zhuojun He, Huimin Guo, Min Shi, Ruijing Liang, Lanlan Liu, Yeneng Dai, Qi Zhao, Ke Liu, Yang Zhou, Yang Zhang, Jian Ren, Bin Ju, Quan Fang, Zhaozhen Li, Pengfei Zhao, Mingbin Zheng, Lintao Cai   +17 more
wiley   +1 more source

Prevalence of presbyopia among social safety net beneficiaries with the cognitive, numeracy and dexterity skills required for smartphone use: a cross-sectional analysis of THRIFT RCT screening data from Kurigram, Bangladesh. [PDF]

BMJ Open
Aftab IB, Chakma T, Pant S, Sigwadhi LN, Shitol SA, Rahman HMM, Alam J, Haque E, Chadalavada HP, Murtaza F, Chan VF, Little JA, Khanna RC, MacKenzie G, Gudwin E, Lohfeld L, Clarke M, Shonchoy A, Congdon N, Rabbani A.   +19 more
europepmc   +1 more source

Distinct Cleavage Trajectories Mediated by DNA and RNA Substrate in Argonaute From Methanocaldococcus Fervens

Advanced Science, EarlyView.
This study characterizes MfAgo, an enzyme exhibiting highly efficient DNA‐guided DNA and RNA cleavage capability. Precise RNA cleavage strictly requires dimerization to stabilize the PIWI‐loop region, while its robust DNA cleavage functions in a dimerization‐independent manner.
Fuyong Huang, Taiyu Chen, Meng Fang, Qinmiao Duanmu, Kangle Mu, Yuqi Bi, Siwei Xu, Xin Tao, Jiening Wang, Shan Wu   +9 more
wiley   +1 more source

The impact of government macroeconomic policies and elections on income smoothing in state-controlled commercial banks: Evidence from the MENA region. [PDF]

PLoS One
Peykani P, Sargolzaei M, Mohagheghnia MJ, Takaloo A, Valimoradi M.   +4 more
europepmc   +1 more source

Effectiveness of structured lactation support and human donor milk banking in German NICUs: a stepped-wedge cluster-randomized trial. [PDF]

BMC Med
Köberlein-Neu J, Dymek NG, Zimmer V, Bommhardt T, Stirner AK, Güldenring I, Ohnhäuser T, Wiesen D, Dresbach T, Scholten N, Neo-MILK Consortium/collaborators.   +10 more
europepmc   +1 more source