Calcium Shock Enables Efficient and Programmable Particle Delivery for Genome Editing Applications
Classical transfection and transduction are inefficient, particularly with confluent cells and organoids, and lack cell type‐specific programmability. This study presents calcium shock (CaSh), a method that dramatically improves particle delivery into single cells, colonies, and organoids.
Nicole Vo +12 more
wiley +1 more source
The implications of European retail banking integration on small and medium-sized enterprises financing. An overview [PDF]
Considering the last few years, the European Union (EU) has became one of the most competitive and integrated economic regions of the world, following a rapid pace of change as a result of an inspired series of initiatives.
Anton, Sorin Gabriel, Avadanei, Andreea
core +1 more source
Firmer foundations for a stronger European Banking Union [PDF]
The move to European Banking Union involving the supervision and resolution of banks at euro-area level was stimulated by the sovereign debt crisis in the euro area in 2012.
Schoenmaker, Dirk
core
The global financial crisis and integration in European retail banking [PDF]
This document is the Accepted Manuscript version of the following article: Aarti Rughoo, and Nicolas Sarantis, 'The global financial crisis and integration in European retail banking', Journal of Banking and Finance, Vol.
Rughoo, Aarti, Sarantis, Nicholas
core +1 more source
Temporal and Cell‐Specific Regulation of Synaptic Homeostasis by the Chromatin Remodeler Chd1
Chd1, the Drosophila homologue of mammalian CHD2 ‐ a gene linked to autism, epilepsy, and intellectual disability, is required for synaptic homeostatic plasticity. Chd1 in glia is necessary for the rapid induction of synaptic homeostasis, whereas Chd1 in motoneurons, muscle, and glia is critical for long‐term maintenance.
Danielle T. Morency +19 more
wiley +1 more source
COVID-19, the European Health Union and the CJEU: Lessons from the Case Law on the Banking Union [PDF]
Oliver Bartlett
openalex +1 more source
Pathogenic Role of FGFR3 Autoantibodies in Small Fiber Neuropathy
Autoantibodies against fibroblast growth factor receptor 3 (FGFR3) are identified as pathogenic drivers of pain in small fiber neuropathy. By binding to sensory neurons in dorsal root ganglia, FGFR3 autoantibodies activate MAPK signaling and induce hyperexcitability and mechanical hypersensitivity, establishing FGFR3 autoantibodies as a therapeutic ...
Lyuba Y. Salih +12 more
wiley +1 more source
The Challenges of the EU Banking Union - will it succeed in dealing with the next financial crisis? Bruges European Economic Policy Briefings 36/2015 [PDF]
The EU Banking Union combines micro- and macro-prudential regulation. It aims at breaking the “doom loop” between banks and sovereign debt, promoting financial stability and mitigating the next financial shock to the real EU economy, at the lowest ...
FALLESEN, Ida-Maria Weirsøe
core +1 more source
Engineered GM1 Intersects Between Mitochondrial and Synaptic Pathways to Ameliorate ALS Pathology
Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease driven by genetic and molecular disruptions affecting energy balance, protein homeostasis, and stress responses in nerve cells. Studies using human and rodent models identified convergent defects in mitochondria and synaptic function.
Federica Pilotto +11 more
wiley +1 more source

