Results 231 to 240 of about 3,026,344 (368)

H3K36me3‐Guided m6A Modification of Oncogenic L1CAM‐AS1 Drives Macrophage Polarization and Immunotherapy Resistance in Hepatocellular Carcinoma

open access: yesAdvanced Science, EarlyView.
L1CAM‐AS1 is identified as a novel H3K36me3‐guided, m6A‐modified long noncoding RNA (lncRNA) in hepatocellular carcinoma (HCC) cells. L1CAM‐AS1 stabilizes RAN protein, enhances M2 macrophages‐released CCL5‐induced nuclear import of RELA, activates the NF‐κB signaling, up‐regulates CCL2 expression and secretion from HCC cells, and enhances M2 ...
Teng Wang   +6 more
wiley   +1 more source

Burning Mouth Syndrome Following Covid Vaccination: A Case Report. [PDF]

open access: yesClin Case Rep
Broachwala M   +4 more
europepmc   +1 more source

Psychometric Evaluation and Calibration of Health-Related Quality of Life Item Banks: Plans for the Patient-Reported Outcomes Measurement Information System (PROMIS)

open access: yesMedical Care, 2007
B. Reeve   +14 more
semanticscholar   +1 more source

A High‐Fidelity RNA‐Targeting Cas13X Downregulates Connexin43 in Macroglia: A Novel Neuroprotective Strategy for Glaucoma

open access: yesAdvanced Science, EarlyView.
This study highlights the role of connexin43 (Cx43) in mediating glia activation and neuroinflammation in glaucoma. Using Cx43 knockout mice, it is shown that macroglial cells‐derived Cx43 modulates microglial activation, proliferation, migration, and polarization.
Guoli Zhao   +17 more
wiley   +1 more source

Planning for a pinniped response during a marine oil spill. [PDF]

open access: yesEnviron Sci Pollut Res Int
Hall AA, Chilvers BL, Weir JS.
europepmc   +1 more source

Tumor‐Associated Glycan Exploits Adenosine Receptor 2A Signaling to Facilitate Immune Evasion

open access: yesAdvanced Science, EarlyView.
This study identifies Globo H ceramide (GHCer) as a novel immune checkpoint molecule that suppresses the activation of conventional T lymphocytes while promoting the differentiation and function of regulatory T cells. The immunosuppressive effects of GHCer are mediated through the activation of the A2AR/cAMP/PKA pathway, which involves its interactions
Jing‐Yan Cheng   +13 more
wiley   +1 more source

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