Results 81 to 90 of about 3,072,717 (390)

Merging: Contemplations on Farming & Ecology from Horseback by Soren Bondrup-Nielsen [PDF]

open access: yes, 2015
Anna Banks reviews Merging: Contemplations on Farming & Ecology from Horseback, by Soren Bondrup ...
Banks, Anna
core   +1 more source

A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner

open access: yesMolecular Oncology, EarlyView.
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp   +13 more
wiley   +1 more source

High prevalence of multi-drug-resistant bacteria in faecal samples from UK passerine birds

open access: yesScientific Reports
Wild birds are a near ubiquitous sight in gardens, offering pleasure to many people through supplementary feeding, song, or other interactions. However, they are also potential carriers of many bacteria, including Campylobacter spp., Salmonella spp ...
Jenny C. Dunn, Simon R. Clegg
doaj   +1 more source

Age, condition and dominance‐related sexual ornament size before and during the breeding season in the black grouse Lyrurus tetrix

open access: yesJournal of Avian Biology, 2018
Male ornaments function as honest cues of male quality in many species and are subject to intra‐ and intersexual selection. These ornaments are generally studied during peak expression, however their size outside the breeding season may determine ...
Sarah Harris   +4 more
doaj   +1 more source

Therapeutic applications of a novel humanized monoclonal antibody targeting chemokine receptor CCR9 in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald   +18 more
wiley   +1 more source

Lectures on Holographic Space Time [PDF]

open access: yes, 2013
Summary of three talks on the Holographic Space Time models of early universe cosmology, particle physics, and the asymptotically de Sitter final state of our universe.Comment: LaTex2e.
Banks, T.
core  

Simultaneous inhibition of TRIM24 and TRIM28 sensitises prostate cancer cells to antiandrogen therapy, decreasing VEGF signalling and angiogenesis

open access: yesMolecular Oncology, EarlyView.
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach   +8 more
wiley   +1 more source

Dimensions of the company’s efficiency

open access: yesAnnals of Spiru Haret University Economic Series, 2010
The synthetic concept of business activity assessment, effectiveness circumscribe their theoretical and practical, a multi-dimensional configuration, which gives supportive and evaluative irrelevant in the field of business.
Gheorghe MANOLESCU, Marinela GEAMĂNU
doaj  

Online gambling and crime: a sure bet? [PDF]

open access: yes, 2012
Despite a growing body of research that is exploring the deleterious social effects of online gambling, there has, to date, been very little empirical research into internet gambling and crime.
Banks, James
core  

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner   +6 more
wiley   +1 more source

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