Results 81 to 90 of about 2,272,414 (343)

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

open access: yesFEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida   +6 more
wiley   +1 more source

DISRUPTING BANKING

open access: yesBusiness Strategy Review, 2014
Can online P2P lenders deliver disruptive innovation to the world of banking?
Jeffery, P, Arnold, D
openaire   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

E.U. VERSUS O.E.C.D. - MIGRATION FLOW UNDER THE LABOUR TAXATION IMPACT [PDF]

open access: yesAnnals of the University of Oradea: Economic Science, 2015
In a world governed by the freedom of movement, production factors – capital, labour and consumption – can “run” from on territory to another bringing along positive and negative effects, just as well.
LAZAR PAULA, Vuta Mariana
doaj  

Reducing bubbles in glass coatings improves electrical breakdown strength [PDF]

open access: yes, 1968
Helium reduces bubbles in glass coatings of accelerator grids for ion thrustors. Fusing the coating in a helium atmosphere creates helium bubbles in the glass.
Banks, B.
core   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

open access: yesFEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman   +4 more
wiley   +1 more source

Human Umbilical Cord Blood–Derived CD34+Cells Can Be Used as a Prophylactic Agent for Experimental Heatstroke

open access: yesJournal of Pharmacological Sciences, 2008
We attempted to assess the prophylactic effect of human umbilical cord blood–derived CD34+cells in experimental heatstroke. Anesthetized rats, 1 day before heat stress, were divided into 2 major groups and given CD34−cells (defined by 1 × 106human cord ...
Wei-Shou Hwang   +5 more
doaj   +1 more source

Bell in the Rain [PDF]

open access: yes, 2016
Poetry by Annabel ...
Banks, Annabel
core   +1 more source

Development of human monoclonal antibodies against TARM1 by yeast display

open access: yesFEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe   +5 more
wiley   +1 more source

“But my horse is well cared for”: A qualitative exploration of cognitive dissonance and enculturation in equestrian attitudes toward performance horses and their welfare

open access: yesAnimal Welfare
There is concern amongst the public, equestrians, animal welfare organisations, and horse-sport governing bodies regarding the welfare of performance horses, but equestrian culture appears slow to change.
Erica Cheung   +2 more
doaj   +1 more source

Home - About - Disclaimer - Privacy