Results 31 to 40 of about 2,356,155 (301)
ABSTRACT Relapsed and/or refractory (R/R) pediatric acute leukemia carries a dismal prognosis, largely driven by chemoresistance to conventional salvage therapy. The BH3‐mimetic venetoclax, combined with chemotherapy or hypomethylating agents, has demonstrated efficacy in small clinical trials.
Katherine S. Colman +9 more
wiley +1 more source
Russia's war against Ukraine, launched on 24 February 2022, had determined new conditions for the existence of Ukrainian society, the state, and all fields of activity. The Bar was no exception.
Oksana Khotynska-Nor, Nana Bakaianova
doaj +1 more source
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo +5 more
wiley +1 more source
In the article are represents theoretical basis of design volume finite elements which can be used at calculation continuous models of bridge systems.
A.S. Raspopov, V.Ye. Artomov
doaj
MAIN TYPES OF MECHANISMS USED AS WINDSHIELD WIPER [PDF]
This paper deals with the main types of windshield wiper mechanisms, consisting of bars and gear links. These mechanisms are classified into two groups: those with constant length arm and those with variable length arm.
Ovidiu ANTONESCU +2 more
doaj +2 more sources
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Facies and depositional settings of the Middle Eocene-Oligocene carbonates in Kutch
Middle Eocene Fulra Limestone and Oligocene Maniyara Fort Formation represent platform carbonate deposits of Kutch at the north-western margin of India.
Santanu Banerjee +2 more
doaj +1 more source
Method of consecutive approximations in the problem of rational distribution of porosity at the pure bend of the bar of rectangular section [PDF]
This article is devoted to a task of rational distribution of porosity on bar section in case of a net bend. The solution of such task will allow to provide the necessary bearing capability in case of decrease in a material capacity of a design.
Shlyakhov S.M., Gavrilov D.Yu.
doaj +1 more source
While functional reconstruction of massive irreparable rotator cuff tears remains a challenge, current techniques aimed at recentering and preventing superior migration of the humeral head allow for clinical and biomechanical improvements in shoulder ...
Maria E Dey Hazra +8 more
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Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source

