Results 41 to 50 of about 3,071,157 (310)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

The association between blood urea nitrogen to serum albumin ratio and 28 day in-hospital mortality in patients with chronic heart failure and sepsis: a pilot retrospective study

Frontiers in Cardiovascular Medicine
AimsThe purpose of this study was to explore the relationship between blood urea nitrogen to serum albumin ratio and 28-day in-hospital mortality in patients with chronic heart failure complicated by sepsis admitted to the intensive care unit (ICU ...
Ali Ma, Ali Ma, Chen Zhang, Chen Zhang, Ying Gong, Ying Gong, Xueping Ma, Xueping Ma, Ning Yan, Ning Yan   +9 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Association of the blood urea nitrogen to serum albumin ratio and 28-day all-cause mortality in patients with cardiac arrest: a retrospective cohort study using the MIMIC-IV database

Frontiers in Cardiovascular Medicine
BackgroundThe blood urea nitrogen to serum albumin ratio (BAR) has been identified as a novel indicator of both inflammatory and nutritional status, exhibiting a correlation with adverse cardiovascular outcomes.ObjectiveTo explore the association between
Gaosheng Zhou, Gaosheng Zhou, Gaosheng Zhou, Yayuan Tan, Yayuan Tan, Yayuan Tan, Xueli Li, Xueli Li, Xueli Li, Yixun Wang, Yixun Wang, Yixun Wang, Dingdeng Wang, Dingdeng Wang, Dingdeng Wang, Min Liu, Min Liu, Min Liu   +17 more
doaj   +1 more source

Flow Unit Model of Channel Sand Body and Its Effect on Remnant Oil Distribution: A Case Study of PI Formation in the Eastern Transition Zone of Daqing Oilfield

Geofluids, 2020
To analyze the effect of various flow units in a channel sand body on remnant oil, we established a connection between various flow unit types and the remnant oil distribution.
Yue Zhang, You-liang Ji, Hui-jian Wen, Shi-zhong Ma, Dong-lai Bai, Bin-chi Zhang, Ben-kang Xing   +6 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Møte i Styret for BIBSYS-konsortiet 19-02-2021 [PDF]

, 2021
Saksdokumenter for møte i Styret for BIBSYS-konsortiet 19/02 2021Saksdokumenter for møte i Styret for BIBSYS-konsortiet 19/02 ...
Unit
core  

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Prognostic Value of Blood Urea Nitrogen to Serum Albumin Ratio in Intensive Care Unit Patients with Lung Cancer

International Journal of General Medicine, 2021
Xiulan Peng,1,* Yali Huang,1,* Haifeng Fu,2,* Zhi Zhang,3 Anbing He,1 Renfeng Luo4 1Department of Oncology, The Second Affiliated Hospital of Jianghan University, Wuhan, Hubei, People’s Republic of China; 2Department of Hepatopancreatobiliary
Peng X, Huang Y, Fu H, Zhang Z, He A, Luo R   +5 more
doaj  

Improved wound management by regulated negative pressure-assisted wound therapy and regulated, oxygen- enriched negative pressure-assisted wound therapy through basic science research and clinical assessment

Indian Journal of Plastic Surgery, 2012
Regulated negative pressure-assisted wound therapy (RNPT) should be regarded as a state-of-the-art technology in wound treatment and the most important physical, nonpharmaceutical, platform technology developed and applied for wound healing in the last ...
Moris Topaz
doaj   +1 more source