Integrating animal experiments, mass spectrometry and network-based approach to reveal the sleep-improving effects of Ziziphi Spinosae Semen and γ-aminobutyric acid mixture [PDF]
Chinese Medicine, 2023 Background Ziziphi Spinosae Semen (ZSS) is a plant widely used as medicine and food in Asian countries due to its numerous health benefits. γ-aminobutyric acid (GABA), a non-proteinaceous amino acid, is one of the major inhibitory neurotransmitters with ...
Airong Ren +7 more
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Multicomponent Crystal of Metformin and Barbital: Design, Crystal Structure Analysis and Characterization [PDF]
Molecules, 2021 The formation of most multicomponent crystals relies on the interaction of hydrogen bonds between the components, so rational crystal design based on the expected hydrogen-bonded supramolecular synthons was employed to establish supramolecular compounds ...
Linhong Cai +5 more
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Xenobiotics Triggering Acute Intermittent Porphyria and Their Effect on Mouse Brain Respiratory Complexes [PDF]
Journal of XenobioticsHeme enzyme dysfunction causes a group of diseases called porphyrias. Particularly, a decrease in porphobilinogen deaminase, involved in the third step of heme biosynthesis, leads to acute intermittent porphyria (AIP).
Johanna Romina Zuccoli +3 more
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Additive-driven microwave crystallization of tyramine polymorphs and salts: a quantum crystallography perspective [PDF]
IUCrJPolymorphism – the ability of a compound to exist in multiple crystalline forms – needs to be carefully considered in the design of functional materials, particularly in the context of cocrystallization.
Szymon Grabowski +7 more
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Dual detection high-speed capillary electrophoresis for simultaneous serum protein analysis and immunoassays [PDF]
Scientific Reports, 2022 Serum protein electrophoresis (SPE) separates serum proteins into bands whose shape and amplitude can alert clinicians to a range of disorders. This is followed by more specific immunoassays to quantify important antigens and confirm a diagnosis. Here we
Prabhavie M. Opallage +2 more
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Whole blood cholinesterase activity in humans and ruminants: Comparison using a modified electrometric method [PDF]
Open Veterinary JournalBackground: Determination of normal whole blood cholinesterase (WBChE) activity is required in the assessment of exposure to organophosphate and carbamate pesticides in humans and animals.
Maha Ahmed Ramadhan +1 more
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Clarifying an Electrometric Method for Determining Blood Cholinesterase Activity: A Scientific Letter [PDF]
Asia Pacific Journal of Medical Toxicology, 2022 In this scientific letter, a modified electrometric method is clarified for rapid and accurate determination of blood cholinesterase (ChE) activity in man and various animal species.
Fouad Mohammad
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Spectroscopic and Molecular Docking Analysis of π-Acceptor Complexes with the Drug Barbital
Applied Sciences, 2022 The drug barbital (Bar) has a strong sedative–hypnotic effect. The intermolecular charge transfer compounds associated with the chemical reactions between Bar and some π acceptors, such as 2,6-dibromoquinone-4-chloroimide (DBQ), tetracyanoquinodimethane (
Abdulhakeem S. Alamri +12 more
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Photochemical Hydrolysis of Barbitals [PDF]
Bulletin of the Chemical Society of Japan, 1968 Abstract The irradiation of barbital (BA) and N,N′-dimethylbarbital (DMBA) in aqueous alkaline media gave diethylacetylurea and N,N′-dimethyldiethylmalonarmide respectively. On the basis of the results of kinetic studies, the above photochemical hydrolyses of BA and DMBA were shown to be an attack of the hydroxide ion on the singlet ...
Y, Otsuji, T, Kuroda, E, Imoto
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Results in Chemistry, 2021 The phosphorylation and dephosphorylation of proteins and other intracellular molecules are important reactions in living systems and are generally controlled by the action of kinases and phosphatases.
Shin Aoki +6 more
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