Results 1 to 10 of about 22,960 (244)

Systematic review and meta-analysis of propofol versus barbiturates for controlling refractory status epilepticus

BMC Neurology, 2019
Background Several studies have compared the efficacy and safety of propofol and barbiturates in the treatment of refractory status epilepticus (RSE). This study aims to quantitatively assess the advantages and disadvantages of propofol and barbiturates ...
Qing Zhang, Yun Yu, Yu Lu, Hongli Yue
doaj   +2 more sources

Propofol‐Related Infusion Syndrome in Paediatrics—Cautious Consideration or Considered Caution? Case Report [PDF]

J Paediatr Child Health
Journal of Paediatrics and Child Health, Volume 62, Issue 6, Page 1075-1080, June 2026.
Michael A. Stokes, Mark A. J. Dexter, Stephen Jacobe, Jonathan R. Egan, Cindy G. Berrueta Rodriguez, Ashfaque Quadir   +5 more
wiley   +2 more sources

Early use of barbiturates is associated with increased mortality in traumatic brain injury patients from a propensity score-based analysis of a prospective cohort.

PLoS ONE, 2022
Barbiturates are proposed as a second/third line treatment for intracranial hypertension in traumatic brain injury (TBI) patients, but the literature remains uncertain regarding their benefit/risk balance.
Maxime Léger, Denis Frasca, Antoine Roquilly, Philippe Seguin, Raphaël Cinotti, Claire Dahyot-Fizelier, Karim Asehnoune, Florent Le Borgne, Thomas Gaillard, Yohann Foucher, Sigismond Lasocki, for AtlanRéa group   +11 more
doaj   +1 more source

Topiramate and other kainate receptor antagonists for depression: A systematic review of randomized controlled trials

Neuropsychopharmacology Reports, 2022
Background Depression is a common disorder that affects patients' quality of life and incurs health system costs. Due to the resistance to treat depression, better understanding of neurophysiology was considered; one of the implications is the ...
Ahmad Shamabadi
doaj   +1 more source

Barbiturates and pyrazolopyridines for the treatment of postpartum depression—repurposing of two drug classes

Frontiers in Pharmacology, 2023
Zulresso (brexanolone) is an aqueous formulation of the neurosteroid, allopregnanolone, and the only FDA-approved medication for the treatment of postpartum depression (PPD).
Alexander B. Horwitz, Robert T. Rubin, Robert T. Rubin   +2 more
doaj   +1 more source

Sedation-Induced Burst Suppression Predicts Positive Outcome Following Traumatic Brain Injury

Frontiers in Neurology, 2021
While electroencephalogram (EEG) burst-suppression is often induced therapeutically using sedatives in the intensive care unit (ICU), there is hitherto no evidence with respect to its association to outcome in moderate-to-severe neurological patients. We
Joel Frohlich, Micah A. Johnson, David L. McArthur, Evan S. Lutkenhoff, John Dell'Italia, Courtney Real, Vikesh Shrestha, Norman M. Spivak, Jesús E. Ruiz Tejeda, Paul M. Vespa, Martin M. Monti, Martin M. Monti   +11 more
doaj   +1 more source

New Methodology for the Synthesis of Thiobarbiturates Mediated by Manganese(III) Acetate

Molecules, 2012
A three step synthesis of various thiobarbiturate derivatives 17–24 was established. The first step is mediated by Mn(OAc)3, in order to generate a carbon-carbon bond between a terminal alkene and malonate.
Patrice Vanelle, Christophe Curti, Ahlem Bouhlel   +2 more
doaj   +1 more source

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

, 2022
Hepatology, EarlyView.
Robert J. Fontana, Iris Liou, Adrian Reuben, Ayako Suzuki, M. Isabel Fiel, William Lee, Victor Navarro   +6 more
wiley   +1 more source

Capacities of Follow-up of the Severity of Acute Barbiturate Intoxications and their Prediction

Общая реаниматология, 2005
Seventy-eight patients with moderate, severe, and fatal (n = 12) acute intoxication with barbiturates, as evidenced by the measurements of their blood concentrations were examined.
I. I. Vorobyeva, A. A. Lavrentyev, G. N. Sukhodolova   +2 more
doaj   +1 more source

Simultaneous Determination of Phenobarbital, Pentobarbital, Amobarbital and Secobarbital in Raw Milk via Liquid Chromatography with Electron Spray Ionization Tandem Mass Spectrometry

Food Science of Animal Resources, 2017
A rapid, sensitive and specific liquid chromatography-tandem mass spectrometry (LC-MS/MS) method was developed for the simultaneous determination of four barbiturates (phenobarbital, pentobarbital, amobarbital and secobarbital) in raw milk.
Huaixiang Tian, Xingxin Zhou, Chen Chen, Yabin He, Haiyan Yu, Xiaoping Zheng   +5 more
doaj   +1 more source