Results 1 to 10 of about 20,745 (198)
Zulresso (brexanolone) is an aqueous formulation of the neurosteroid, allopregnanolone, and the only FDA-approved medication for the treatment of postpartum depression (PPD).
Alexander B. Horwitz +2 more
doaj +3 more sources
Barbiturates are proposed as a second/third line treatment for intracranial hypertension in traumatic brain injury (TBI) patients, but the literature remains uncertain regarding their benefit/risk balance.
Maxime Léger +11 more
doaj +1 more source
Background Depression is a common disorder that affects patients' quality of life and incurs health system costs. Due to the resistance to treat depression, better understanding of neurophysiology was considered; one of the implications is the ...
Ahmad Shamabadi
doaj +1 more source
Sedation-Induced Burst Suppression Predicts Positive Outcome Following Traumatic Brain Injury
While electroencephalogram (EEG) burst-suppression is often induced therapeutically using sedatives in the intensive care unit (ICU), there is hitherto no evidence with respect to its association to outcome in moderate-to-severe neurological patients. We
Joel Frohlich +11 more
doaj +1 more source
New Methodology for the Synthesis of Thiobarbiturates Mediated by Manganese(III) Acetate
A three step synthesis of various thiobarbiturate derivatives 17–24 was established. The first step is mediated by Mn(OAc)3, in order to generate a carbon-carbon bond between a terminal alkene and malonate.
Patrice Vanelle +2 more
doaj +1 more source
Capacities of Follow-up of the Severity of Acute Barbiturate Intoxications and their Prediction
Seventy-eight patients with moderate, severe, and fatal (n = 12) acute intoxication with barbiturates, as evidenced by the measurements of their blood concentrations were examined.
I. I. Vorobyeva +2 more
doaj +1 more source
Background Several studies have compared the efficacy and safety of propofol and barbiturates in the treatment of refractory status epilepticus (RSE). This study aims to quantitatively assess the advantages and disadvantages of propofol and barbiturates ...
Qing Zhang, Yun Yu, Yu Lu, Hongli Yue
doaj +1 more source
AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury
Hepatology, EarlyView.
Robert J. Fontana +6 more
wiley +1 more source
A rapid, sensitive and specific liquid chromatography-tandem mass spectrometry (LC-MS/MS) method was developed for the simultaneous determination of four barbiturates (phenobarbital, pentobarbital, amobarbital and secobarbital) in raw milk.
Huaixiang Tian +5 more
doaj +1 more source
Barbiturate-refractory epilepsy: safe schedule for therapeutic substitution
Barbiturates are considered first line antiepileptic drugs in third world countries due to traditional and economic reasons. This prospective uncontrolled study of 52 patients aged 15 to 64 years (mean 24) demonstrates that patients who become refractory
Ana Maria Gorz +2 more
doaj +1 more source

