Results 1 to 10 of about 129,948 (248)

Differences in the Effects of Pentobarbital Anesthetic and Combination of Medetomidine Hydrochloride, Midazolam, and Butorphanol Tartrate Anesthetic on Electroretinogram in Spontaneously Diabetic Torii Fatty Rats

Biomedicine Hub, 2022
Purpose: The aim of this study was to investigate the effects of different anesthetic agents on electroretinograms (ERGs) in Spontaneously Diabetic Torii fatty rats (SDT fatty rats).
Tetsuya Hasegawa, Rina Takagi, Yoshiaki Tanaka, Takeshi Ohta, Masami Shinohara, Yasushi Kageyama, Tomohiko Sasase, Shin-ichi Muramatsu, Toshikatsu Kaburaki, Akihiro Kakehashi   +9 more
doaj   +1 more source

Spectroscopic Investigations of Pentobarbital Interaction with Transthyretin

Journal of Spectroscopy, 2013
Transthyretin (TTR) aggregation has been characterized to be responsible for several amyloid diseases. Fourier transform infrared (FTIR) spectroscopy, fluorescence, and atomic force microscopy (AFM) are used to investigate secondary structure changes in ...
Saqer M. Darwish, Jafar Ghithan, Musa M. Abuteir, Mariam Faroun, Mahmoud M. Abu-hadid   +4 more
doaj   +1 more source

Spike timing rigidity is maintained in bursting neurons under pentobarbital-induced anesthetic conditions

Frontiers in Neural Circuits, 2016
Pentobarbital potentiates γ-aminobutyric acid (GABA)-mediated inhibitory synaptic transmission by prolonging the open time of GABAA receptors. However, it is unknown how pentobarbital regulates cortical neuronal activities via local circuits in vivo.
Risako Kato, Masanori Yamanaka, Eiko Yokota, Noriaki Koshikawa, Masayuki Kobayashi   +4 more
doaj   +1 more source

Pentobarbital-Induced Myocardial Stunning in Status Epilepticus Requiring Extracorporeal Membrane Oxygenation: A Case Report and Literature Review

Case Reports in Critical Care, 2016
Introduction. Mild hypotension is a well-recognized complication of intravenous pentobarbital; however fulminant cardiopulmonary failure has not been previously reported. Case Report.
Tapan Kavi, Donna Molaie, Michael Nurok, Axel Rosengart, Shouri Lahiri   +4 more
doaj   +1 more source

Effects of anesthetics on the renal sympathetic response to anaphylactic hypotension in rats. [PDF]

PLoS ONE, 2014
The autonomic nervous system plays an important role in rat anaphylactic hypotension. It is well known that sympathetic nerve activity and cardiovascular function are affected by anesthetics.
Lingling Sun, Mamoru Tanida, Mofei Wang, Yuhichi Kuda, Yasutaka Kurata, Toshishige Shibamoto   +5 more
doaj   +1 more source

Effects of Propofol on Electrocardiogram Measures in Mice

Journal of Pharmacological Sciences, 2014
.: We investigated the anesthetic effects of propofol on the electrocardiogram (ECG) in mice. We also compared the effects of isoflurane (2%) inhalation anesthesia, intraperitoneal propofol (50 or 100 mg/kg), and pentobarbital (50 mg/kg) on ECG in mice ...
Tomohiro Shintaku, Takayoshi Ohba, Hidetoshi Niwa, Tetsuya Kushikata, Kazuyoshi Hirota, Kyoichi Ono, Yasushi Matsuzaki, Tadaatsu Imaizumi, Kenji Kuwasako, Daisuke Sawamura, Manabu Murakami   +10 more
doaj   +1 more source

Severe pentobarbital poisoning treated after two sessions of intermittent hemodialysis: A case report

JEM Reports
Background: Pentobarbital is a short-acting barbiturate that can cause life-threatening central nervous system, respiratory, and cardiovascular depression if massively overdosed.
Sohma Miyamoto, Shutaro Isokawa, Norio Otani, Masatoshi Miyamoto, Yoshito Kamijo   +4 more
doaj   +1 more source

Stability-Indicating Assay for the Determination of Pentobarbital Sodium in Liquid Formulations

International Journal of Analytical Chemistry, 2015
A stability-indicating assay by reversed-phase high performance liquid chromatography (RP-HPLC) method was developed for the determination of pentobarbital sodium in oral formulations: a drug used for infant sedation in computed tomography (CT) or ...
Myriam Ajemni, Issa-Bella Balde, Sofiane Kabiche, Sandra Carret, Jean-Eudes Fontan, Salvatore Cisternino, Joël Schlatter   +6 more
doaj   +1 more source

Effects of First- and Second-Generation Histamine-H1-Receptor Antagonists on the Pentobarbital-Induced Loss of the Righting Reflex in Streptozotocin-Induced Diabetic Mice

Journal of Pharmacological Sciences, 2005
The second-generation histamine-H1-receptor antagonists, such as epinastine and cetirizine, are used as non-sedating antihistamines for treating allergic symptoms due to their poor ability to penetrate blood-brain barrier.
Junzo Kamei, Shoko Hirano, Shigeo Miyata, Akiyoshi Saitoh, Kenji Onodera   +4 more
doaj   +1 more source

Stability of Sodium Pentobarbital 5w/v% Aqueous Solution During Short‐Term Chilled and Ambient‐Temperature Storage

Veterinary Medicine and Science
The COVID‐19 pandemic made it difficult to obtain pharmaceutical‐grade injectable anaesthetics used in animal experiments in Japan. To address this problem, it is worth the effort to evaluate whether the use of non‐pharmaceutical‐grade sodium ...
Masakazu Dohi, Kayoko Ueda, Yoshinori Yamagiwa, Atsuko Yamashita, Yuji Sakamoto   +4 more
doaj   +1 more source