Results 31 to 40 of about 22,960 (244)

Crystal structure of 5-hydroxy-5-propylbarbituric acid

open access: yesActa Crystallographica Section E: Crystallographic Communications, 2015
Molecules of the title compound, C7H10N2O4, systematic name 5-hydroxy-5-propylpyrimidine-2,4,6(1H,3H,5H)-trione, form a hydrogen-bonded framework which is based on three independent hydrogen bonds, N—H...O(carbonyl), N—H...O(hydroxy) and O—H...O(carbonyl)
Thomas Gelbrich, Ulrich J. Griesser
doaj   +1 more source

Organocatalytic Formal (3+2+1)‐Cycloaddition of Allenoates, Michael Acceptors, and Carbaldehydes

open access: yesChemistry – A European Journal, EarlyView.
The use of secondary amine Lewis base organocatalysts allows for the unprecedented activation of allenoates for formal (3+2+1)‐cycloadditions with Michael acceptors and aromatic carbaldehydes. ABSTRACT Employing secondary amines as covalently interacting Lewis basic organocatalysts allows for the activation of electron‐deficient allenes (allenoates ...
David Naderer   +5 more
wiley   +1 more source

Effects of barbiturates on A1 adenosine receptors of rat brain [PDF]

open access: yes, 1985
Barbiturates inhibit binding of radioligands to A 1(Ri) adenosine receptors of rat brain membranes. This inhibition is dose-dependent and stereospecific and occurs in the range of pharmacologically active concentrations. The displacement of radiolabelled
Klotz, Karl-Norbert   +2 more
core  

On the local anaesthetic effect of barbiturates

open access: yes, 1969
Controversy exists about whether the free acid (non-ionized) or the anionic (ionized) form of barbiturates abolish the excitation of nerves. The experiments made showed that sodium pentobarbitone and sodium phenobarbitone are more effective at pH 6·8 ...
C P Bianchi, G Suarez-Kurtz, P Krupp
core   +1 more source

Exploring Cerumen as an Alternative Matrix for Drug Detection and Quantification: Method Development and Application in Clinical Samples

open access: yesDrug Testing and Analysis, EarlyView.
An LC–MS/MS method was developed for the detection of 33 psychoactive medications in cerumen (earwax) and applied to the samples of 60 psychiatric inpatient volunteers. The findings highlighted the utility of cerumen as an innovative biospecimen in clinical toxicological analysis.
Dimitrios Phaedon Kevrekidis   +5 more
wiley   +1 more source

Potentiometric measurement of barbituric acid by integration of supramolecular receptors into ChemFETs

open access: yesSensing and Bio-Sensing Research, 2021
Potentiometric sensing devices were prepared based on ion-selective membranes (ISM) containing Hamilton-type receptors incorporated into polymer membranes.
Grace M. Kuhl   +4 more
doaj   +1 more source

Cyclodextrins as Chiral Selectors in Capillary Electrophoresis—Recent Developments in Understanding Analyte Complexation and Applications in Pharmaceutical Analysis

open access: yesELECTROPHORESIS, EarlyView.
Cyclodextrins are the most often applied chiral selectors in CE enantioseparations. In combination with NMR spectroscopy and molecular modeling, studies for an understanding of chiral recognition underlying enantioseparations have been performed.
Gerhard K. E. Scriba
wiley   +1 more source

Barbiturates depress vagal motor pathway to ferret trachea at ganglia

open access: yes, 1982
To determine which site in the vagal motor pathway to airway smooth muscle is most sensitive to depression by barbiturates, we recorded isometric muscle tension in vitro and stimulated the vagal motor pathway at four different sites before and after ...
B. E. Skoogh   +3 more
core   +1 more source

NMDAR‐antibody encephalitis: Seizure semiology and EEG findings

open access: yesEpileptic Disorders, EarlyView.
Abstract Background N‐methyl‐D‐aspartate receptor antibody encephalitis (NMDAR‐Ab‐E) is an autoantibody‐mediated disorder, characterized by acute development of neuropsychiatric symptoms, seizures, movement disorders, and autonomic instability. Objectives To describe acute seizure semiology and electroencephalogram (EEG) findings in patients with a ...
Maria Emilia C. Andraus   +6 more
wiley   +1 more source

Rapid visualization of fingerprints on various surfaces using ZnO superstructures prepared via simple combustion route

open access: yesJournal of Science: Advanced Materials and Devices, 2018
A simple solution combustion route has been used to prepare ZnO nanopowders (NPs) using different barbiturates (Barbituric acid, 1, 3-dimethyl barbiturates and 2-thiobarbiturates) as fuels.
N.H. Deepthi   +6 more
doaj   +1 more source

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