Results 41 to 50 of about 24,812 (221)

Increased GABA(A) receptor ε-subunit expression on ventral respiratory column neurons protects breathing during pregnancy. [PDF]

open access: yesPLoS ONE, 2012
GABAergic signaling is essential for proper respiratory function. Potentiation of this signaling with allosteric modulators such as anesthetics, barbiturates, and neurosteroids can lead to respiratory arrest.
Keith B Hengen   +7 more
doaj   +1 more source

Cenobamate use in super‐refractory status epilepticus: A report of three cases

open access: yesEpileptic Disorders, EarlyView.
Abstract Objectives Super‐refractory status epilepticus (SRSE) is a neurological emergency with high morbidity and mortality. Cenobamate, a novel antiseizure medication, may be helpful in managing SRSE, but evidence is limited. Methods This retrospective case series reports the use of cenobamate as add‐on therapy in the management of three cases of ...
Marina Romozzi   +11 more
wiley   +1 more source

The buccal absorption of some barbiturates

open access: yes, 1971
The buccal absorptions of five barbiturates have been determined over the pH range 3 to 9. The absorptions increased as the pH decreased until pH 5.5 when they remained constant.
A H BECKETT, A C MOFFAT
core   +1 more source

Determination of barbiturates in hair samples by using a validated UHPLC-HRMS method: application in investigation of drug-facilitated sexual assault

open access: yesForensic Sciences Research, 2019
In recent years, benzodiazepines and benzodiazepine-like drugs are the most common substances associated with drug-facilitated sexual assaults (DFSA); however, barbiturates are also detected occasionally.
Di Wen   +8 more
doaj   +1 more source

Assessment of Controlled Substance Distribution to U.S. Veterinary Teaching Institutions From 2006 to 2019

open access: yesFrontiers in Veterinary Science, 2020
Objective: To evaluate the changing pattern of distribution of Schedule II and III opioids, barbiturates, and stimulants to veterinary educational institutions in the United States.Design: Longitudinal study.Sample: Veterinary teaching institutions that ...
Brian J. Piper   +4 more
doaj   +1 more source

Brain pathology caused in the neonatal macaque by short and prolonged exposures to anticonvulsant drugs

open access: yesNeurobiology of Disease, 2021
Barbiturates and benzodiazepines are potent GABAA receptor agonists and strong anticonvulsants. In the developing brain they can cause neuronal and oligodendroglia apoptosis, impair synaptogenesis, inhibit neurogenesis and trigger long-term ...
Kevin K. Noguchi   +12 more
doaj   +1 more source

NMDAR‐antibody encephalitis: Seizure semiology and EEG findings

open access: yesEpileptic Disorders, EarlyView.
Abstract Background N‐methyl‐D‐aspartate receptor antibody encephalitis (NMDAR‐Ab‐E) is an autoantibody‐mediated disorder, characterized by acute development of neuropsychiatric symptoms, seizures, movement disorders, and autonomic instability. Objectives To describe acute seizure semiology and electroencephalogram (EEG) findings in patients with a ...
Maria Emilia C. Andraus   +6 more
wiley   +1 more source

On the local anaesthetic effect of barbiturates

open access: yes, 1969
Controversy exists about whether the free acid (non-ionized) or the anionic (ionized) form of barbiturates abolish the excitation of nerves. The experiments made showed that sodium pentobarbitone and sodium phenobarbitone are more effective at pH 6·8 ...
C P Bianchi, G Suarez-Kurtz, P Krupp
core   +1 more source

The effect of barbiturates in porphyria turcica

open access: yesThe Turkish Journal of Pediatrics, 1963
Case histories of three patients with porphyria turcica are presented. Two patients manifested the disease in a quiescent state, one was acutely ill.
İhsan Doğramacı   +3 more
doaj   +1 more source

Overview: eutanasia and methods of antanasia of animals

open access: yesНауковий вісник Львівського національного університету ветеринарної медицини та біотехнологій імені С.З. Ґжицького: Серія Ветеринарні науки, 2022
The attention of modern society to euthanasia has increased because many centuries ago, a social phenomenon was established, associated not only with the achievements of medical science but also with changing values of the individual and society ...
S. Nichiporuk   +2 more
doaj   +1 more source

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