Results 11 to 20 of about 24,812 (221)

Barbiturates: Tranquilizers [PDF]

open access: yes, 2018
Barbiturates are minor tranquilizer. Commonly prescribes minor tranquilizers name is Phenobarbiturates. It is the much older tranquilizer, which act on the central neural system and act as depressant.
S. Sreeremya, Sreeremya, S.
core   +1 more source

Effects of barbiturates on A1 adenosine receptors of rat brain [PDF]

open access: yes, 1985
Barbiturates inhibit binding of radioligands to A 1(Ri) adenosine receptors of rat brain membranes. This inhibition is dose-dependent and stereospecific and occurs in the range of pharmacologically active concentrations. The displacement of radiolabelled
Klotz, Karl-Norbert   +2 more
core   +2 more sources

Organocatalytic Formal (3+2+1)-Cycloaddition of Allenoates, Michael Acceptors, and Carbaldehydes. [PDF]

open access: yesChemistry
The use of secondary amine Lewis base organocatalysts allows for the unprecedented activation of allenoates for formal (3+2+1)‐cycloadditions with Michael acceptors and aromatic carbaldehydes. ABSTRACT Employing secondary amines as covalently interacting Lewis basic organocatalysts allows for the activation of electron‐deficient allenes (allenoates ...
Naderer D   +5 more
europepmc   +2 more sources

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

open access: yes, 2022
Hepatology, EarlyView.
Robert J. Fontana   +6 more
wiley   +1 more source

Buthalital and methitural – 5,5-substituted derivatives of 2-thiobarbituric acid forming the same type of hydrogen-bonded chain

open access: yesActa Crystallographica Section E: Crystallographic Communications, 2017
The molecule of buthalital, (I) [systematic name: 5-(2-methylpropyl)-5-(prop-2-en-1-yl)-2-sulfanylidene-1,3-diazinane-4,6-dione], C11H16N2O2S, exhibits a planar pyrimidine ring, whereas the pyrimidine ring of methitural, (II) [systematic name: 5-(1 ...
Thomas Gelbrich, Ulrich J. Griesser
doaj   +1 more source

A Letter About Phenobarbital Poisoning [PDF]

open access: yesInternational Journal of Medical Toxicology and Forensic Medicine, 2020
The ever-increasing sensitivity of humans and living in a world full of stress and anxiety have led to the increased consumption of painkillers and sleeping pills. Barbiturates, which are among the most important sedatives, are regularly used by ordinary
Zahra Ataee , Maryam Sayyari Doughabadi
doaj   +1 more source

Flavin Catalysts in Organic Synthesis

open access: yesAngewandte Chemie, EarlyView.
Flavins and their congeners are potent catalysts for organic synthesis inspired by enzymatic transformations. In addition to catalysis in the flavin ground state via covalent intermediates, the excited singlet and triplet states unlock applications including photooxidation, photoreduction, and energy transfer via sensitization.
Jan Freudenberg, Golo Storch
wiley   +2 more sources

The use of barbiturate-induced coma during cerebrovascular neurosurgery procedures: A review of the literature

open access: yesBrain Circulation, 2015
Barbiturates are indicated for use during vascular neurosurgery procedures such as carotid surgery, arteriovenous malformation (AVM) surgery, cerebral aneurysm surgery, extracranial-intracranial bypass, and following significant bleeding due to AVMs or ...
Nathaniel R Ellens   +2 more
doaj   +1 more source

Recognition of anesthetic barbiturates by a protein binding site: a high resolution structural analysis. [PDF]

open access: yesPLoS ONE, 2012
Barbiturates potentiate GABA actions at the GABA(A) receptor and act as central nervous system depressants that can induce effects ranging from sedation to general anesthesia.
Simon Oakley   +7 more
doaj   +1 more source

Antibacterial Barbituric Acid Analogues Inspired from Natural 3-Acyltetramic Acids; Synthesis, Tautomerism and Structure and Physicochemical Property-Antibacterial Activity Relationships

open access: yesMolecules, 2015
The synthesis, tautomerism and antibacterial activity of novel barbiturates is reported. In particular, 3-acyl and 3-carboxamidobarbiturates exhibited antibacterial activity, against susceptible and some resistant Gram-positive strains of particular ...
Yong-Chul Jeong, Mark G. Moloney
doaj   +1 more source

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