Results 211 to 220 of about 38,601 (270)

An Algorithm for Opioid and Barbiturate Reduction in the Acute Management of Headache in the Emergency Department

Headache, 2017
To develop and implement an algorithm for the management of headaches presenting to the emergency department (ED) in order to decrease the frequency of opioid and barbiturate treatment both acutely as well as on discharge.
Z. Ahmed, Dimitrios A. Nacopoulos, S. John, Nancy D. Papesh, D. Levine, C. Bamford   +5 more
semanticscholar   +1 more source

Asymmetric Construction of Highly Functionalized Spirobarbiturate-Cyclopentenes through Chiral Phosphine-Catalyzed [3+2] Annulation of Morita–Baylis–Hillman Carbonates with Barbiturate-Derived Alkenes

, 2016
A multifunctional chiral phosphine-catalyzed enantioselective [3+2] annulation of Morita–Baylis–Hillman carbonates with barbiturate-derived alkenes has been achieved under mild conditions, providing a variety of chiral spirobarbiturate-cyclopentenes in ...
Yang Liu, Wenjun Yang, Yang Wu, Biming Mao, Xing Gao, Honglei Liu, Zhanhu Sun, Yumei Xiao, Hongchao Guo   +8 more
semanticscholar   +1 more source

Organocatalytic [3+2] Cycloadditions of Barbiturate‐Based Olefins with 3‐Isothiocyanato Oxindoles: Highly Diastereoselective and Enantioselective Synthesis of Dispirobarbiturates

, 2016
Catalyzed by a Cinchona-based thiourea, the [3+2] cycloadditions of barbiturate-based olefins with 3-isothiocyanatooxindoles proceeded readily, and furnished dispirobarbiturates in excellent chemical yields with excellent diastereo- and ...
Hong‐Wu Zhao, Ting Tian, Hailiang Pang, Bo Li, Xiao-Qin Chen, Zhao Yang, W. Meng, Xiu-qing Song, Yu-Di Zhao, Yue-Yang Liu   +9 more
semanticscholar   +1 more source

Extracorporeal treatment for barbiturate poisoning: recommendations from the EXTRIP Workgroup.

American Journal of Kidney Diseases, 2014
The EXTRIP (Extracorporeal Treatments in Poisoning) Workgroup conducted a systematic review of barbiturate poisoning using a standardized evidence-based process to provide recommendations on the use of extracorporeal treatment (ECTR) in patients with ...
R. Mactier, Martin Laliberté, J. Mardini, M. Ghannoum, V. Lavergne, S. Gosselin, R. Hoffman, T. Nolin   +7 more
semanticscholar   +1 more source

Formation of a hydrogen-bonded barbiturate [2]-rotaxane.

Organic Letters, 2014
Interlocked structures containing the classic Hamilton barbiturate binding motif comprising two 2,6-diamidopyridine units are reported for the first time.
A. Tron, P. Thornton, Mathias Rocher, Henri‐Pierre Jacquot de Rouville, J. Desvergne, B. Kauffmann, T. Buffeteau, D. Cavagnat, J. H. Tucker, N. McClenaghan   +9 more
semanticscholar   +1 more source

Economic Evaluation of Decompressive Craniectomy Versus Barbiturate Coma for Refractory Intracranial Hypertension Following Traumatic Brain Injury*

Critical Care Medicine, 2014
Objectives:Decompressive craniectomy and barbiturate coma are often used as second-tier strategies when intracranial hypertension following severe traumatic brain injury is refractory to first-line treatments. Uncertainty surrounds the decision to choose
Aziz S. Alali, David M J Naimark, Jefferson R. Wilson, R. Fowler, D. Scales, Eyal Golan, T. Mainprize, J. Ray, A. Nathens   +8 more
semanticscholar   +1 more source

GABA‐Benzodiazepine‐Barbiturate Receptor Interactions

Journal of Neurochemistry, 1981
The major inhibitory neurotransmitter in mammalian brain, y-aminobutyric acid (GABA), exerts its effects through increased postsynaptic membrane permeability to chloride ions (McBurney and Barker, 1978; Nistri et a]., 1980).
R. Olsen
semanticscholar   +1 more source

Lidocaine barbiturate: a promising material for second harmonic generation

, 2013
Lidocaine barbiturate is a novel organic, mechanically and optically stable non-linear optical material, which shows effects higher than that of KDP. The engineered material, which belongs to the group of organic salts containing polarizable components ...
M. Gryl, M. Kozieł, K. Stadnicka, I. Matulková, Ivan Němec, N. Tesařová, P. Němec   +6 more
semanticscholar   +1 more source

Design of barbiturate-nitrate hybrids that inhibit MMP-9 activity and secretion.

Journal of Medicinal Chemistry, 2012
We describe a new type of barbiturate-based matrix metalloproteinase (MMP) inhibitor incorporating a nitric oxide (NO) donor/mimetic group (series 1).
Jun Wang, S. O’Sullivan, S. Harmon, Raymond D. Keaveny, M. Radomski, C. Medina, J. Gilmer   +6 more
semanticscholar   +1 more source

Enhanced elimination in acute barbiturate poisoning – A systematic review

Clinical toxicology, 2011
Context. Despite a worldwide decline in barbiturate use, cases of acute poisoning with severe toxicity are still noted, particularly in developing countries.
D. Roberts, N. Buckley
semanticscholar   +1 more source