Results 141 to 150 of about 279,790 (255)

Isolable C‐Phosphonio‐Boratavinyl Anion

Angewandte Chemie, EarlyView.
A persistent C‐phosphonio boratavinyl anion was successfully synthesized. This boron‐containing vinyl lithium, featuring a vinyl carbon with an excessively high negative charge, exhibits remarkable nucleophilic and basic character, which was demonstrated by the result of a rapid reaction with H2 at RT.
Huihui Xu, Aurora Rodríguez‐Álvarez, Md Jabed Hossain, Antoine Baceiredo, Eddy Maerten, Nathalie Saffon‐Merceron, Vicenç Branchadell, Tsuyoshi Kato   +7 more
wiley   +2 more sources

Genetic Modifiers of ABCA1 Activity Interact with APOE Isoforms to Mediate Alzheimer's Disease Risk

Annals of Neurology, EarlyView.
Objective ATP‐binding cassette transporter A1 (ABCA1) has been associated with Alzheimer's disease (AD), but the mechanisms by which it impacts disease risk are unknown. ABCA1 is known to bind apolipoprotein E (ApoE) and catalyze apolipoprotein lipidation.
Andrés Peña‐Tauber, Ricardo Hernández Arriaza, Dylan Reil, Manon Muntaner, Junyoung Park, Benjamin Grenier‐Boley, Marc Hulsman, Philippe Amouyel, Céline Bellenguez, Camille Charbonnier, Jean‐François Deleuze, Orio Dols‐Icardo, John Hardy, Henne Holstege, Gaël Nicolas, Simon Mead, Michael Wagner, Alfredo Ramirez, Rebecca Sims, John van Swieten, Julie Willams, Jean‐Charles Lambert, Chaitan Khosla, Yann Le Guen, Michael D Greicius   +24 more
wiley   +1 more source

Monitoring Antiseizure Medication Change Using Ultra Long‐Term Electroencephalogram: A Multicenter Study

Annals of Neurology, EarlyView.
Objective Medication dose adjustments are common in treatment‐resistant epilepsy, but lack robust evidence, and patient‐reported seizure diaries have known limitations. We assessed whether ultra long‐term subcutaneous electroencephalogram (sqEEG) improves detection of seizure frequency changes after antiseizure medication adjustments.
Pedro F. Viana, Matthew McWilliam, Johannes Koren, Christina Duarte, Tamara Lisy, Christoph Baumgartner, Karl Rössler, Matthias Tomschik, Adriana Celdrán de Castro, Rodrigo Rocamora, Laura Vilella, Guido Rubboli, Sigge Weisdorf, Cecilia Friedrichs‐Maeder, Troels W. Kjaer, Sanchita Bhatia, Dympna McAleer, Khalid Hamandi, Deborah Spencer, Rajiv Mohanraj, Mark P. Richardson   +20 more
wiley   +1 more source

The Role of Zn–Hf Site Proximity and Oxygen Vacancies for Methanol Formation Over ZnHfOx Catalysts Under CO2 Hydrogenation Conditions

Angewandte Chemie, EarlyView.
ZnHfOx catalysts enable highly selective hydrogenation of CO2 to methanol over a wide range of Zn contents, as the Zn‐VO‐Hf active motif (VO = oxygen vacancy) exists not only in solid solution‐type ZnHfOx for low Zn contents (≤ 35 mol%), but also as HfOx cluster/single atom decorated ZnO surfaces for Zn contents > 95 mol%.
Alexander Oing, Diana Piankova, Jean C. Villa‐Arpi, Muhammad Helmi Risansyauqi, Hector Prats, Felix Donat, Paula M. Abdala, Aleix Comas‐Vives, Christoph R. Müller   +8 more
wiley   +2 more sources

Infections in Patients With Cytokine Release Syndrome/Immune Effector Cell-Associated Neurotoxicity Syndrome Following Chimeric Antigen Receptor T-Cell Therapy. [PDF]

Open Forum Infect Dis
Gallardo-Pizarro A, Ariño M, Lopera C, Martinez-Urrea A, Terrones-Campos C, Castiella-Aranzasti A, González-Navarro EA, Albiol N, Teijon-Lumbreras C, Pitart C, Marcos MÁ, Ortíz-Maldonado V, Mensa J, Delgado J, Urbano-Ispizua Á, Fernández de Larrea C, Soriano A, Martinez-Cibrian N, Castro P, Garcia-Vidal C.   +19 more
europepmc   +1 more source

Barcelona 2016 : presentación de Barcelona

, 2017
Gabinet Tècnic de Programació, Departament d'Estudis i Programació   +1 more
openaire   +2 more sources

Das fehlende Glied der Ferrocenophan‐Chemie: Isolierung eines Carba[1]Ferrocenophans

Angewandte Chemie, EarlyView.
Die Synthese und Isolierung eines kristallinen Carba[1]Ferrocenophans wird berichtet. Ein einzelnes Kohlenstoffatom ist das bislang kleinste Verbrückungsmotiv, das in ein Ferrocenophan eingebaut werden konnte. Dies resultiert in einem Diederwinkel der Ebenen der Cyclopentadienylringe von 36.7°, was entsprechend die größte Abwinkelung relativ zu ...
Aylin Feuerstein, Sergi Danés, Kathrin Kolling, Bernd Morgenstern, Markus Gallei, André Schäfer   +5 more
wiley   +1 more source

Defect‐Guided Assembly of Aperiodic and Flexible Metal–Organic Frameworks From Pre‐Formed Cages

Angewandte Chemie, EarlyView.
A cage‐directed strategy is used to program topologically correlated defects and induce aperiodicity in HKUST‐1‐type MOFs. A missing carboxylate group in the linker drives the formation of Cu‐vacancy domains, while Rh(II) cages spatially confine these defects.
Francisco Sánchez‐Férez, Akim Khobotov‐Bakishev, Borja Ortín‐Rubio, Cornelia von Baeckman, Laura Hernández‐López, Alba Cortés‐Martínez, Robert A. I. Paraoan, Roberto Boada, Judith Juanhuix, Felipe Gándara, Andrew L. Goodwin, Arnau Carné‐Sánchez, Daniel Maspoch   +12 more
wiley   +2 more sources

Barcelona 2017 : presentación de Barcelona

, 2018
Gabinet Tècnic de Programació, Oficina Municipal de Dades   +1 more
openaire   +2 more sources

Unraveling A4GALT Mechanism and Its Modulation With Adamantyl‐Galactosylceramide Analogues: Advancing Fabry Disease Therapeutic Strategies

Angewandte Chemie, EarlyView.
A 310‐helix‐mediated conformational switch promotes a front‐face SNi‐like catalysis by human A4GALT. Mechanism‐guided design identifies AdaGalCer as a selective modulator of globotriaosylceramide (Gb3) biosynthesis, opening a clear route toward new Fabry disease therapeutics.
Nicky de Koster, Òscar Vidal‐Gironès, Rowan de Graaf, Ken Kok, Lindsey T. Lelieveld, Jackelien Hoogervorst, Maria J. Ferraz, José Pablo Rivas‐Fernández, Rob F. Lammers, Herman S. Overkleeft, Johannes M. F. G. Aerts, Rolf G. Boot, Carme Rovira, Marta Artola   +13 more
wiley   +2 more sources