Results 121 to 130 of about 252,506 (348)

Neuid: A Novel Neuron‐Enriched LncRNA that Connects Epigenetic Gene Silencing to Alzheimer's Disease

open access: yesAdvanced Science, EarlyView.
ABSTRACT The increasing evidence that non‐coding RNAs can become deregulated during pathogenesis is dramatically expanding the space for drug discovery beyond the protein‐coding genome. Long noncoding RNAs (lncRNAs) are emerging as key regulators of cellular function, yet most remain uncharacterized.
Ranjit Pradhan   +17 more
wiley   +1 more source

The Importance of Forgetting: Limiting Memory Improves Recovery of Topological Characteristics from Neural Data

open access: yes, 2017
We develop of a line of work initiated by Curto and Itskov towards understanding the amount of information contained in the spike trains of hippocampal place cells via topology considerations.
Chowdhury, Samir   +2 more
core   +2 more sources

De Novo Design and Directed Evolution Refinement of Mirror‐Image Protein Binders Targeting Interleukin‐4

open access: yesAdvanced Science, EarlyView.
This study presents the de novo design and directed evolution of a mirror‐image D‐protein inhibitor targeting human interleukin‐4 (IL‐4). The engineered molecule exhibits nanomolar binding affinity for IL‐4 and effectively inhibits IL‐4–mediated signaling.
Liqing Xu   +7 more
wiley   +1 more source

Tracking Chart 2005 PVH Corp, Sri Lanka 10007093D [PDF]

open access: yes, 2005
This document is part of a digital collection provided by the Martin P. Catherwood Library, ILR School, Cornell University, pertaining to the effects of globalization on the workplace worldwide.
Fair Labor Association
core   +1 more source

Dualities in persistent (co)homology

open access: yes, 2010
We consider sequences of absolute and relative homology and cohomology groups that arise naturally for a filtered cell complex. We establish algebraic relationships between their persistence modules, and show that they contain equivalent information.
Chazal F   +7 more
core   +4 more sources

10x barcode fastq of Anolis allisoni used for Supernova de novo assembly

open access: green, 2022
Shunsuke Kanamori   +5 more
openalex   +1 more source

Understanding and Overcoming Antibody‐Drug Conjugate Resistance: Biological Mechanisms and Emerging Analytical Frameworks in Breast Cancer

open access: yesAdvanced Science, EarlyView.
Antibody–drug conjugates (ADCs) transform breast cancer therapy, yet resistance limits their durability. Emerging evidence reveals that ADC failure is not solely tumor‐intrinsic but shaped by dynamic tumor–microenvironment interactions that alter drug delivery, processing, and response.
Minji Seo, Jangsoon Lee, Naoto T. Ueno
wiley   +1 more source

A new species of Pangora Moore 1879 (Lepidoptera: Erebidae) from India based on DNA barcoding and internal genitalia

open access: yesJournal of Asia-Pacific Biodiversity
The genus Pangora Moore (1879) is endemic to south Asia, with four known species distributed in India, Sri Lanka, and Nepal. The current study offers the scientific community the first mitochondrial genome sequence of the known species Pangora matherana (
P.K. Adarsh   +4 more
doaj   +1 more source

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