Results 211 to 220 of about 62,315 (312)

One‐step generation of heritable mitochondrial DNA multiplex‐engineered rats using DddA‐derived cytosine base editor

open access: yesAnimal Models and Experimental Medicine, EarlyView.
We established that mixed DdCBE microinjection is an efficient, heritable, and precise strategy for generating multiplex mtDNA mutant rats. This advancement significantly expands the utility of DdCBEs for mitochondrial disease modeling, providing a robust platform for exploring the pathogenic mechanisms of complex mtDNA mutations and developing ...
Xu Zhang   +14 more
wiley   +1 more source

An integrative taxonomic approach reveals unexplored diversity in Croatian planarians. [PDF]

open access: yesFront Zool
Vila-Farré M   +13 more
europepmc   +1 more source

Anti‐inflammatory and osteogenic effects of transcutaneous electrical nerve stimulation in knee osteoarthritis rats via the regulation of the intestinal microbiota

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Transcutaneous electrical nerve stimulation (TENS) improved knee osteoarthritis (KOA) in rats by regulating interleukin‐1β (IL‐1β), IL‐6, and IL‐8 expressions and the bone morphogenetic protein 2 (BMP‐2)/transforming growth factor β (TGF‐β) signaling pathway.
Yan Sun   +6 more
wiley   +1 more source

Comparative analysis of monoterpene indole alkaloid composition and genotypic variation in Thai <i>Mitragyna speciosa</i>. [PDF]

open access: yesFront Plant Sci
Ransden KE   +6 more
europepmc   +1 more source

HapAsmbl: A reference‐aided pipeline for assembling haplotypes in Nanopore amplicon sequence data of polymorphic populations

open access: yesApplications in Plant Sciences, EarlyView.
Abstract Premise Advances in long‐read sequencing offer new possibilities to investigate haplotype diversity across multiple genes in plants and other taxa through multi‐locus, long‐read amplicon sequencing (multi‐locus LRAS). Despite this progress, there is a notable absence of dedicated bioinformatics pipelines for assembling diploid haplotypes of ...
Ayodele Oluwaseyi Fakoya   +4 more
wiley   +1 more source

DNA Barcoding and Chemical Profile Using UHPLC, GC-MS and LC-MS/QTOF of <i>Mitragyna speciosa</i> Variation and Allied Species for Quality Control of Kratom Materials. [PDF]

open access: yesPlants (Basel)
Anantaworasakul P   +11 more
europepmc   +1 more source

Leveraging target enrichment and genome skimming (Hyb‐Seq) of herbarium collections to unlock timber DNA barcoding

open access: yesApplications in Plant Sciences, EarlyView.
Abstract Premise DNA barcoding for timber species identification requires comprehensive reference datasets, informative DNA barcodes, and cost‐effective protocols. We developed a workflow leveraging Hyb‐Seq (target capture sequencing and genome skimming) to address these challenges, and we tested it on four genera from the mahogany family (Meliaceae ...
Sidonie Bellot   +14 more
wiley   +1 more source

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