Results 91 to 100 of about 13,450,182 (319)
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Refugees and social theory: from the politics of “bare life” to refugees as political subjects
Acta Academica, 2014 This article explores theoretical literature on refugees, noting a significant distinction between an abstract body of work critiquing the politics of humanitarianism and an ethnographic literature focused on refugee subjects. As I argue, refugees should
Christian A. Williams
semanticscholar +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Beckett and Bare Life: Post-war Political Subjectivity in Molloy [PDF]
Estudios Irlandeses, 2019 What can Beckett offer political theory concerned with subjecthood in the aftermath of the Nazi concentration camps? I suggest in this essay that Molloy provides a literary terrain through which to explore the collapse of the Enlightenment and the ...
John Parker Evans
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Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Historical Dispossession in Adam Thorpe’s Ulverton
Études Britanniques Contemporaines, 2017 The purpose of this article will be to analyse in Adam Thorpe’s first novel, Ulverton (1992), the implications of the notion of ‘dispossession’, both in terms of politics and ethics, in relation to the (un)recordability of England’s modern history, that ...
Alexandre Privat
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Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Nuda vida y goce. // Bare life and jouissance.
Affectio Societatis, 2010 From the point of view that connects politics and psychoanalysis, the aim of this essay is to investigate the causes of the annihilation of the subject in the totalitarian regimes, making him a victim of power, reduced to a bare life. This question leads
Laura Arias.
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