Results 71 to 80 of about 59,630 (306)
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Historical Dispossession in Adam Thorpe’s Ulverton
The purpose of this article will be to analyse in Adam Thorpe’s first novel, Ulverton (1992), the implications of the notion of ‘dispossession’, both in terms of politics and ethics, in relation to the (un)recordability of England’s modern history, that ...
Alexandre Privat
doaj +1 more source
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Rethinking Zombie Apocalypses: Legal Limbo, Bare Life, and Posthuman
Anbei Cheng
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Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Informality and survival in Ukraine's nuclear landscape: Living with the risks of Chernobyl
Recent debates on informal economic activities have partially switched away from a pure monetary logic towards a more complex one, embedded in long term relations and reckoning with non materialistic paradigms.
Thom Davies, Abel Polese
doaj +1 more source
Teori Filsafat Politik Agamben dalam Karya Sastra: Bare Life dan Homo Sacer
Damay Rahmawati, Ecclisia Sulistyowati
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Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source

