Results 91 to 100 of about 15,465 (199)

Baricitinib Successfully Treated a Teenager with Refractory Livedoid Vasculopathy: A Case Report and Literature Review [PDF]

Chenxi Liu, Ying-Ying Jin, Xiqiong Han, Hua Huang, Shengfang Bao, Xuemei Xu, Liping Wang, Yanliang Jin Department of Rheumatology and Immunology, Shanghai Children’s Medical Center, Shanghai Jiao Tong University School of Medicine, Shanghai, 200127 ...
Jin YY, Huang H, Han X, Liu C, Bao S, Xu X, Jin Y, Wang L   +7 more
core  

Treatment strategies for interstitial granulomatous dermatitis: Systematic review and expert opinion

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Systematic review of 108 studies with a total of 182 patients with interstitial granulomatous dermatitis (IGD). IGD was frequently associated with systemic conditions or drug exposure. Management includes careful medication review and prompt withdrawal of potential triggers. Corticosteroids (systemic and topical) were commonly effective, while biologic
Francesco Bellinato, Sara Salvagno, Chiara Colato, Paolo Gisondi, Giampiero Girolomoni   +4 more
wiley   +1 more source

Efficacy, retention, and safety of baricitinib in real-life: HUR-BIO monocentric experience

Ulusal Romatoloji Dergisi
Objective: This study evaluates the effectiveness, retention rate and safety of baricitinib, including a comparison between baricitinib and a tumour necrosis factor inhibitor (adalimumab) in a real-life cohort of patients with rheumatoid arthritis (RA).
Mustafa Ekici, İrem Yıldız İçli, Ece Ersal Deregözü, Emre Bilgin, Zehra Özsoy, Gizem Ayan, Gül Sandal Uzun, Erdinç Ünaldı, Büşra Fırlatan Yazgan, Gözde Sevgi Kart Bayram, Buğu Bulat, Levent Kılıç, Ali Akdoğan, Şule A. Bilgen, Sedat Kiraz, İhsan Ertenli   +15 more
doaj   +1 more source

Baricitinib ameliorates skin fibrosis via direct fibroblast suppression and endothelial exosome-mediated paracrine signaling

Arthritis Research & Therapy
Background Novel therapies are urgently needed for diffuse cutaneous systemic sclerosis (dcSSc). Aberrant JAK/STAT signaling drives fibrosis, but JAK inhibitors’ effects on vascular pathology and potential synergy with endothelial-derived exosomes remain
Zhanying Hou, Xiufeng Zhao, Fang Liu, Shi Xu   +3 more
doaj   +1 more source

Fifty-Two-Week Results of Clinical and Imaging Assessments of a Patient with Rheumatoid Arthritis Complicated by Systemic Sclerosis with Interstitial Pneumonia and Type 1 Diabetes despite Multiple Disease-Modifying Antirheumatic Drug Therapy That Was Successfully Treated with Baricitinib: A Novel Case Report

Case Reports in Rheumatology, 2019
Baricitinib is a Janus kinase 1/2 (JAK1/2) inhibitor used in the treatment of rheumatoid arthritis. A 71-year-old woman with rheumatoid arthritis complicated by systemic sclerosis and type 1 diabetes that were resistant to multiple disease-modifying ...
Yuya Fujita, Masao Nawata, Atsushi Nagayasu, Kazuki Someya, Kazuyoshi Saito, Yoshiya Tanaka   +5 more
doaj   +1 more source

Effectiveness of baricitinib in severe alopecia areata in real life [PDF]

Introduction: Alopecia areata (AA) is an autoimmune condition characterized by non-scarring hair loss. The Janus kinase (JAK)signal transducer and activator of transcription (STAT) pathway is believed to play a central role in the autoimmune inflammatory
Aleid, Nouf M.
core   +1 more source

Atrophic Papulosis: A Systematic Review of Pediatric Cases

Pediatric Dermatology, EarlyView.
ABSTRACT Background Atrophic papulosis is a rare occlusive vasculopathy that can present with isolated cutaneous disease or with systemic involvement. Pediatric cases are uncommon, and existing reports are heterogeneous, limiting understanding of disease patterns, timing of organ involvement, and outcomes.
Ou Jia Emilie Wang, Alennie Lopez, Renee Gabrielle Fajardo, Richard I. Crawford, Joseph M. Lam   +4 more
wiley   +1 more source

Baricitinib Withdrawal and Retreatment in Patients With Severe Alopecia Areata [PDF]

ImportanceBaricitinib has demonstrated efficacy for treating severe alopecia areata in adults. There is currently limited information about the need for continuous therapy after achieving scalp hair regrowth.ObjectiveTo report results from the randomized
Ko, Justin, Piraccini, Bianca Maria, Yu, Guanglei, Ball, Susan, Mesinkovska, Natasha A, Dutronc, Yves, Liu, Chunyuan, Kwon, Ohsang, Vañó-Galván, Sergio, Somani, Najwa, King, Brett   +10 more
core   +1 more source

Baricitinib plus Remdesivir for Hospitalized Adults with Covid-19

, 2021
BACKGROUND Severe coronavirus disease 2019 (Covid-19) is associated with dysregulated inflammation. The effects of combination treatment with baricitinib, a Janus kinase inhibitor, plus remdesivir are not known.
Frank, M., Nielsen, H., Taiwo, B., Mularski, R. A., Cardoso, A., Nayak, S. U., Lye, D. C., Amin, A. N., Saklawi, Y., Deye, G. A., Erdmann, N., Wolfe, C. R., Watanabe, M., Ruiz-Palacios, G. M., Kim, E. -S., Taylor, B. S., Iovine, N. M., Branche, A. R., Ko, E. R., El Sahly, H. M., Cantos, V. D., Mehta, A. K., Kim, Hong Bin, Tapson, V., Ahuja, N., Davey, R. T., Kline, S., Ghazaryan, V., Cohen, S. H., Sandkovsky, U., Elie, M. -C., Kalil, A. C., Makowski, M., Green, M., Burgess, T. H., Kim, NAM JOONG, Beigel, J. H., Sweeney, D. A., Jain, M. K., Finberg, R. W., Bonnett, T., the ACTT-2 Study Group Member, Marconi, V. C., Oh, Myoung Don, Engemann, J. J., Larson, L. A., Hsieh, L., Paules, C. I., Dempsey, W., Rouphael, N. G., Ponce, P. O., Arguinchona, H., Oh, M., Dodd, L. E., Patterson, T. F., Luetkemeyer, A. F., Park, Wan Beom, Tomashek, K. M., Jackson, P. E. H., de Bono, S., Tan, S. Y., Billings, J., Proschan, M., Pineda, J. Regalado, Ferreira, J.   +64 more
core   +1 more source

Periodontitis and rheumatoid arthritis—Global efforts to untangle two complex diseases

Periodontology 2000, EarlyView.
Abstract Understanding the impact of oral health on rheumatoid arthritis (RA) will inform how best to manage patients with both periodontitis and RA. This review seeks to provide an update on interventional and mechanistic investigations, including a brief summary of European Research programs investigating the link between periodontitis and RA. Recent
Isabel Lopez‐Oliva, Jennifer Malcolm, Shauna Culshaw   +2 more
wiley   +1 more source