Results 31 to 40 of about 18,762 (211)

Diabetes, hypertension, and cardiovascular disease: clinical insights and vascular mechanisms [PDF]

, 2018
Hypertension and type 2 diabetes are common comorbidities. Hypertension is twice as frequent in patients with diabetes compared with those who do not have diabetes.
Guzik, Tomasz J., Petrie, John R., Touyz, Rhian M.   +2 more
core   +1 more source

Palmoplantar Pustulosis-like Eruption Induced by Baricitinib for Treatment of Rheumatoid Arthritis

European Journal of Case Reports in Internal Medicine, 2019
Objectives: Baricitinib is an orally active Janus kinase (JAK) inhibitor used in the treatment of moderate to severe rheumatoid arthritis (RA). Materials and methods: Here, we report the case of a 56-year-old Caucasian male diagnosed with RA who ...
Dimitra Koumaki, Vasiliki Koumaki, George Bertsias, Eleni Lagoudaki, George Bertsias   +4 more
doaj   +1 more source

Real-world comparative effectiveness and safety of tofacitinib and baricitinib in patients with rheumatoid arthritis

Arthritis Research & Therapy, 2021
Objective To compare the efficacy and safety of tofacitinib and baricitinib in patients with RA in a real-world setting. Methods A total of 242 patients with RA who were treated with tofacitinib (n = 161) or baricitinib (n = 81) were enrolled.
Naoki Iwamoto, Shuntaro Sato, Shota Kurushima, Toru Michitsuji, Shinya Nishihata, Momoko Okamoto, Yoshika Tsuji, Yushiro Endo, Toshimasa Shimizu, Remi Sumiyoshi, Takahisa Suzuki, Akitomo Okada, Tomohiro Koga, Shin-ya Kawashiri, Keita Fujikawa, Takashi Igawa, Toshiyuki Aramaki, Kunihiro Ichinose, Mami Tamai, Hideki Nakamura, Akinari Mizokami, Tomoki Origuchi, Yukitaka Ueki, Katsumi Eguchi, Atsushi Kawakami   +24 more
doaj   +1 more source

Recommendations for coronavirus infection in rheumatic diseases treated with biologic therapy. [PDF]

, 2020
The Coronavirus-associated disease, that was first identified in 2019 in China (CoViD-19), is a pandemic caused by a bat-derived beta-coronavirus, named SARS-CoV2.
Ansari, Aftab A, Ceribelli, Angela, De Santis, Maria, Gershwin, M Eric, Motta, Francesca, Ridgway, William M, Selmi, Carlo   +6 more
core  

Emerging Therapies for the Treatment of Psoriasis [PDF]

, 2012
Psoriasis is an immune-mediated disease that affects 1%–2% of the European and North American population. While topical agents such as corticosteroids and vitamin D derivatives are prescribed for mild disease, they are generally unable to adequately ...
Alan Menter, Antoinette Day, Mahir Patel, Richard B. Warren   +3 more
core   +1 more source

Baricitinib treatment for hospitalized patients with severe COVID-19 on invasive mechanical ventilation: a propensity score-matched and retrospective analysis

Frontiers in Medicine
IntroductionBaricitinib is a selective inhibitor of Janus kinase (JAK)1 and JAK2, which is associated with clinical improvement in non-severe COVID-19 patients.
Yanxiong Mao, Anyi Guo, Ying Zhang, Jianxing Lai, Dian Yuan, Hao Zhang, Wenqi Diao, Weisong Chen, Fugui Yan   +8 more
doaj   +1 more source

Efficacy and safety of baricitinib and tocilizumab in hospitalized patients with COVID-19: A comparison using systematic review and meta-analysis

Frontiers in Pharmacology, 2022
Objective: This review was performed to compare the efficacy and safety among hospitalized patients with COVID-19 who received baricitinib and those who received tocilizumab independently with placebo or the standard of care (SOC).Methods: Relevant ...
Jerin Jose Cherian, Madhavi Eerike, Bhavani Shankara Bagepally, Saibal Das, Saibal Das, Samiran Panda   +5 more
doaj   +1 more source

Severe Atopic Dermatitis In Spain: A Real-Life Observational Study [PDF]

, 2019
Objective: To determine the epidemiology and characterize the treatment prescribed for severe atopic dermatitis (AD) in children/adults in usual clinical practice.
Armario Hita, José Carlos, Navarro-Artieda, Ruth, Sicras-Mainar, Antoni   +2 more
core   +2 more sources

Baricitinib ameliorates inflammatory and neuropathic pain in collagen antibody-induced arthritis mice by modulating the IL-6/JAK/STAT3 pathway and CSF-1 expression in dorsal root ganglion neurons

Arthritis Research & Therapy
Background Janus kinase (JAK) inhibitors, such as baricitinib, are widely used to treat rheumatoid arthritis (RA). Clinical studies show that baricitinib is more effective at reducing pain than other similar drugs.
Kenta Makabe, Hiroyuki Okada, Naohiro Tachibana, Hisatoshi Ishikura, Norihito Ito, Masaru Tanaka, Ryota Chijimatsu, Asuka Terashima, Fumiko Yano, Meiko Asaka, Dai Yanagihara, Shuji Taketomi, Takumi Matsumoto, Sakae Tanaka, Yasunori Omata, Taku Saito   +15 more
doaj   +1 more source

A RETROSPECTIVE CASE CONTROL STUDY TO ASSESS THE EFFECTIVENESS OF BARICITINIB AMONG MODERATE TO SEVERE COVID-19 CASES; EXPERIENCE FROM A SOUTH INDIAN TERTIARY CARE CENTRE

International Journal of Infectious Diseases, 2023
Intro: Dysregulated inflammation plays a key role in the development of severe SARS-CoV-2 infection. One of the key cellular signaling pathway involved in the inflammatory response is JAK/STAT signaling. Among the hospitalized Covid patients with hypoxia
N.T. Kambhampati, D. Sathyapalan, M. Moni, G. Pillai M, R. Moosa   +4 more
doaj   +1 more source