Results 121 to 130 of about 22,336 (265)

Research Communication: Prevalence of Asymptomatic Premalignant Oesophageal Lesions in Patients With Fanconi Anaemia

open access: yesAlimentary Pharmacology &Therapeutics, Volume 62, Issue 9, Page 939-943, November 2025.
Clinically relevant endoscopic findings in asymptomatic Fanconi Anemia patients. ABSTRACT Fanconi anaemia (FA), a rare genetic disorder of DNA repair, predisposes to squamous cell carcinomas of head, neck and oesophagus. We assessed the value of screening esophagogastroduodenoscopy (EGD) in 20 asymptomatic adults (median age 23.5, 65% female) with FA ...
Joshua A. Sloan   +7 more
wiley   +1 more source

Cytochromes P450 are Expressed in Proliferating Cells in Barrett's Metaplasia

open access: yesNeoplasia: An International Journal for Oncology Research, 1999
The expression of cytochromes P450 (CYP) in Barrett's esophagus and esophageal squamous mucosa was investigated. Esophagectomy specimens from 23 patients were examined for CYP expression of CYP1A2, CYP3A4, CYP2C9/10, and CYP2E1 by immunohistochemical ...
Steven J. Hughes   +7 more
doaj   +1 more source

Aminolevulinic acid-induced photodynamic therapy: safe and effective ablation of dysplasia in Barrett’s esophagus [PDF]

open access: bronze, 2000
Roger Ackroyd   +5 more
openalex   +1 more source

A Role for High Mobility Group Box 1 (HMGB1) Release in the Pathogenesis of Gastroesophageal Reflux Disease

open access: yesNeurogastroenterology &Motility, Volume 37, Issue 11, November 2025.
Incubation of esophageal epithelial cells with a weakly acidic (pH 5) bile salt (deoxycholic acid) induces translocation of HMGB1 from the nucleus to the cytosol, and its subsequent release from the cell. This process can be ameliorated by pre‐treatment with the antioxidant, curcumin.
Tom Leech   +4 more
wiley   +1 more source

Keratin 7 expression as an early marker of reflux-related columnar mucosa without intestinal metaplasia in the esophagus [PDF]

open access: yes, 2009
BACKGROUND: The role of Barrett esophagus in carcinogenesis is widely accepted, but the significance of esophageal columnar mucosa without histological intestinal metaplasia, known as columnar-lined esophagus, is debated. MATERIAL/METHODS: We studied 128
Aragona, F.   +7 more
core  

Comprehensive Insights into Tracheoesophageal Fistula Pathophysiology, Diagnosis, Treatment, and Future Directions

open access: yesAdvanced Science, Volume 12, Issue 37, October 6, 2025.
Tracheoesophageal fistula (TEF), a pathological trachea‐esophagus connection, arises congenitally or from malignancy/radiotherapy/trauma, causing aspiration and malnutrition. Diagnosis utilizes imaging and endoscopy. Treatment ranges from endoscopic stenting to surgical repair and conservative management.
Gang Li   +10 more
wiley   +1 more source

Intravital microscopy contribution to cancer: From preclinical to human studies

open access: yesClinical and Translational Discovery, Volume 5, Issue 5, October 2025.
Intravital microscopy is a powerful tool able to study in detail the microvasculature of live tissues. Given recent advances in its technology, it has now been translated to human use with examples in this review ranging from melanoma to brain tumours. Abstract Intravital microscopy enables dynamic and real‐time visualisation of microscopic structures ...
Diogo Moniz‐Garcia   +5 more
wiley   +1 more source

Aggressive Adenocarcinoma of the Cervical Esophagus: Importance of a Multidisciplinary Approach

open access: yesCase Reports in Gastrointestinal Medicine, 2012
Adenocarcinoma of the cervical esophagus is a rare tumor, in comparison to adenocarcinoma of the distal esophagus which is on the rise and is often associated with Barrett's esophagus. We present a case of aggressive cervical esophageal adenocarcinoma in
Adedayo Fashoyin   +7 more
doaj   +1 more source

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