Results 11 to 20 of about 22,336 (265)

Proton Pump Inhibitors: The Culprit for Barrett’s Esophagus? [PDF]

Frontiers in Oncology, 2015
(BE)-dysplasia-carcinoma (EAC) sequence (8, 11); however, a mechanistic explanation of the proposed scenario is currently missing. We hypothesize that (i) a temporally sustained albeit transient increase in the gastric pH, may cause bile salts to become soluble in the proximity of the lower esophageal sphincter (LES) where they may mobilize to the ...
Anca D. Dobrian, Omran Alsalahi
openaire   +4 more sources

Risk factors associated with Barrett's esophagus in hospitalized patients

Revista de la Facultad de Medicina Humana, 2021
Objective: The objective of this article is to carry out a systematic review of scientific articles that reveal the risk factors associated with Barrett's esophagus in hospitalized patients.
Gerard Martín Gómez
doaj   +1 more source

Three-tiered risk stratification model to predict progression in Barrett's esophagus using epigenetic and clinical features. [PDF]

PLoS ONE, 2008
Barrett's esophagus predisposes to esophageal adenocarcinoma. However, the value of endoscopic surveillance in Barrett's esophagus has been debated because of the low incidence of esophageal adenocarcinoma in Barrett's esophagus.
Fumiaki Sato, Zhe Jin, Karsten Schulmann, Jean Wang, Bruce D Greenwald, Tetsuo Ito, Takatsugu Kan, James P Hamilton, Jian Yang, Bogdan Paun, Stefan David, Alexandru Olaru, Yulan Cheng, Yuriko Mori, John M Abraham, Harris G Yfantis, Tsung-Teh Wu, Mary B Fredericksen, Kenneth K Wang, Marcia Canto, Yvonne Romero, Ziding Feng, Stephen J Meltzer   +22 more
doaj   +1 more source

High Expression of Cathepsin E in Tissues but Not Blood of Patients with Barrett’s Esophagus and Adenocarcinoma [PDF]

Annals of Surgical Oncology, 2014
Cathepsin E (CTSE), an aspartic proteinase, is differentially expressed in the metaplasia-dysplasia-neoplasia sequence of gastric and colon cancer. We evaluated CTSE in Barrett's esophagus (BE) and cancer because increased CTSE levels are linked to improved survival in several cancers, and other cathepsins are up-regulated in BE and esophageal ...
Sarah J. Lord, Sarah J. Lord, Dan Falkenback, Natalia K. Botelho, Antony Wettstein, David C. Whiteman, Oliver M. Fisher, Melissa L. Thomas, Yuri V. Bobryshev, Angelique Levert-Mignon, Reginald V. Lord, Araluen Freeman   +11 more
openaire   +6 more sources

Role of artificial intelligence in diagnosing Barrett’s esophagus-related neoplasia [PDF]

Clinical Endoscopy, 2023
Barrett’s esophagus is associated with an increased risk of adenocarcinoma. Thorough screening during endoscopic surveillance is crucial to improve patient prognosis.
Michael Meinikheim, Helmut Messmann, Alanna Ebigbo   +2 more
doaj   +1 more source

Reduced risk of Barrett’s esophagus in statin users: case–control study and meta-analysis [PDF]

, 2016
Background: Use of statins has been associated with a reduced incidence of esophageal adenocarcinoma in population-based studies. However there are few studies examining statin use and the development of Barrett’s esophagus.
A Dubecz, A Goldberg, AP Thrift, BC Jacobson, D Fang, D Lin, DM Nguyen, E Cheong, E Long, F Kastelein, F Yousef, G Balasubramanian, GM Masclee, I Beales, Ian L. P. Beales, IL Beales, IL Beales, IL Beales, IL Beales, IL Beales, Inna Vardi, JH Rubenstein, K Yokota, L Alexandre, L Alexandre, L Alexandre, Leanne Dearman, LM Brown, M Dovizio, M Sikkema, N Sivarasan, NJ Shaheen, O Ogunwobi, OO Ogunwobi, OO Ogunwobi, OO Ogunwobi, PE Lazzerini, S Singh, S Zhang, T Broughton, T Broughton, T Nguyen, TK Desai, TV Macfarlane, X Wu, Y Fang, Yoon Loke, ZB Omer   +47 more
core   +1 more source

Mucosa-Associated Microbiota in Barrett's Esophagus, Dysplasia, and Esophageal Adenocarcinoma Differ Similarly Compared With Healthy Controls

Clinical and Translational Gastroenterology, 2020
INTRODUCTION: Alterations in the composition of the human gut microbiome and its metabolites have been linked to gut epithelial neoplasia. We hypothesized that differences in mucosa-adherent Barrett's microbiota could link to risk factors, providing risk of progression to neoplasia. Methods:
Peter, Shajan, Pendergraft,, Amanda, VanDerPol, William, Wilcox, Mel, Baig, Kondal R. Kyanam Kabir, Morrow, Casey, Izard, Jacques, Mannon, Peter J.   +7 more
openaire   +2 more sources

Is It Barrett's Esophagus or Gastric Heterotopia

Case Reports in Gastroenterology, 2014
Columnar epithelium in the distal part of the esophagus is generally related to Barrett's esophagus. Barrett's esophagus is a well-known premalignant lesion for adenocarcinoma of the esophagus.
Zeynel Mungan
doaj   +1 more source

Transcribed ultraconserved noncoding RNAs (T-UCR) are involved in Barrett's esophagus carcinogenesis. [PDF]

, 2014
Barretts esophagus (BE) involves a metaplastic replacement of native esophageal squamous epithelium (Sq) by columnar-intestinalized mucosa, and it is the main risk factor for Barrett-related adenocarcinoma (BAc).
Baffa, R, Bornschein, J, Braconi, C, Croce, CM, D'Angelo, E, Dall'Olmo, L, Fassan, M, Galasso, M, Gasparini, P, Nuovo, GJ, Pizzi, M, Realdon, S, Rugge, M, Souza, RF, Valeri, N, Vicentini, C, Volinia, S, Zaninotto, G   +17 more
core   +4 more sources

Germline variant in MSX1 identified in a Dutch family with clustering of Barrett’s esophagus and esophageal adenocarcinoma [PDF]

, 2017
The vast majority of esophageal adenocarcinoma cases are sporadic and caused by somatic mutations. However, over the last decades several families have been identified with clustering of Barrett’s esophagus and esophageal adenocarcinoma. This observation
Biermann, K. (Katharina), Dinjens, W.N.M. (Winand), IJcken, W.F.J. (Wilfred) van, Klein, A. (Annelies) de, Lanschot, J.J.B. (Jan) van, Marion, R. (Ronald) van, Nistelrooij, A.M.J. (Annemarie) van, Spaander, M.C.W. (Manon), Wagner, A. (Anja), Wijnhoven, B.P.L. (Bas)   +9 more
core   +1 more source