Results 51 to 60 of about 22,336 (265)

Beyond Field Effect: Analysis of Shrunken Centroids in Normal Esophageal Epithelia Detects Concomitant Esophageal Adenocarcinoma

Bioinformatics and Biology Insights, 2007
Background and Aims Because of the extremely low neoplastic progression rate in Barrett's esophagus, it is difficult to diagnose patients with concomitant adenocarcinoma early in their disease course.
Florin M. Selaru, Suna Wang, Jing Yin, Karsten Schulmann, Yan Xu, Yuriko Mori, Alexandru V. Olaru, Fumiaki Sato, James P. Hamilton, John M. Abraham, Paul Schneider, Bruce D. Greenwald, Jan Brabender, Stephen J. Meltzer M.D.   +13 more
doaj   +2 more sources

The prevalence of gastric heterotopia of the proximal esophagus is underestimated, but preneoplasia is rare - correlation with Barrett’s esophagus

BMC Gastroenterology, 2017
Background The previously reported prevalence of gastric heterotopia in the cervical esophagus, also termed inlet patch (IP), varies substantially, ranging from 0.18 to 14%.
Ulrich Peitz, Michael Vieth, Matthias Evert, Jovana Arand, Albert Roessner, Peter Malfertheiner   +5 more
doaj   +1 more source

HOXA13 in etiology and oncogenic potential of Barrett’s esophagus

Nature Communications, 2021
Barrett’s esophagus is a pro-oncogenic lesion in the proximal gastrointestinal tract, but with a distal colon-like morphology. Here the authors report that the distal HOX gene HOXA13 is expressed in Barrett’s esophagus and in single cells of the ...
Vincent T. Janmaat, Kateryna Nesteruk, Manon C. W. Spaander, Auke P. Verhaar, Bingting Yu, Rodrigo A. Silva, Wayne A. Phillips, Marcin Magierowski, Anouk van de Winkel, H. Scott Stadler, Tatiana Sandoval-Guzmán, Luc J. W. van der Laan, Ernst J. Kuipers, Ron Smits, Marco J. Bruno, Gwenny M. Fuhler, Nicholas J. Clemons, Maikel P. Peppelenbosch   +17 more
doaj   +1 more source

The Role of Pepsinogenes and Some Intestinal Hormones in Pathogenesis of Gastroesophageal Reflux Disease [PDF]

, 2018
80 patients with gastroesophageal reflux disease (GERD) were examined. The diagnosis of GERD was based on the history of the disease, complaints of patients, the results of daily monitoring of pH in the lower third of the esophagus, data of ...
Boichuk, V. (Vira)
core   +2 more sources

Cancer Risk in Patients With Systemic Sclerosis: A Nationwide Cohort Study in South Korea 2004 to 2021

Arthritis Care &Research, EarlyView.
Objective Systemic sclerosis (SSc) is a rare autoimmune disease characterized by tissue fibrosis, vasculopathy, and immune dysregulation. Our objectives were to quantify the overall and site‐specific cancer risks in patients with SSc compared to the general population, examine temporal trends in cancer incidence following SSc diagnosis, and explore ...
Jihyun Na, Su Jin Choi, Sojeong Park, Minae Park, Doo‐Ho Lim   +4 more
wiley   +1 more source

Advanced Image‐Guidance and Surgical‐Navigation Techniques for Real‐Time Visualized Surgery

Advanced Science, EarlyView.
This review comprehensively summarizes advances in surgical navigation, covering both established and emerging intraoperative imaging technologies. It highlights mechanisms, advantages, limitations, and clinical applications, while emphasizing interdisciplinary collaboration.
Xiaoxiao Fan, Xiaolong Liu, Qiming Xia, Guoqiao Chen, Jiaxi Cheng, Zhaoqi Shi, Yifeng Fang, Parikshit Asutosh Khadaroo, Jun Qian, Hui Lin   +9 more
wiley   +1 more source

Volumetric laser endomicroscopy and its application to Barrett's esophagus: results from a 1,000 patient registry. [PDF]

, 2019
Volumetric laser endomicroscopy (VLE) uses optical coherence tomography (OCT) for real-time, microscopic cross-sectional imaging. A US-based multi-center registry was constructed to prospectively collect data on patients undergoing upper endoscopy during
Berzin, T, Cash, B, Chang, K, DeMeester, S, Di Palma, JA, Diehl, D, Ganguly, E, Gonda, T, Gordon, S, Gress, F, Hagen, J, Hasan, M, Hawes, R, Hyder, S, Jobe, B, Joshi, V, Kahaleh, M, Kedia, P, Khara, H, Komatsu, Y, Konda, V, Lee, C, Lipham, J, Malik, Z, Mashimo, H, McKinley, M, Navaneethan, U, Oh, D, Pleskow, D, Poneros, J, Rodriguez, R, Rothstein, R, Samarasena, J, Sawhney, M, Schnoll-Sussman, F, Sejpal, DV, Sethi, A, Sharaiha, R, Sharzehi, K, Siddiqui, UD, Singh, S, Smith, MS, Tarnasky, P, Thakkar, S, Trindade, AJ, Wallace, M, Waxman, I, Wolfsen, H   +47 more
core  

The molecular changes driving the carcinogenesis in Barrett's esophagus: Which came first, the chicken or the egg? [PDF]

, 2013
Esophageal adenocarcinoma originates from columnar metaplastic epithelium of the distal esophagus. Various steps for this carcinogenetic process are known.
BAZAN, Viviana, Bertani, A, BRONTE, Giuseppe, CABIBI, Daniela, CICERO, Giuseppe, FIORENTINO, Eugenio, RIZZO, Sergio, RUSSO, Antonio   +7 more
core   +1 more source

Nationwide Survey of the Surgical Treatment for Hiatal Hernia in Japan

Annals of Gastroenterological Surgery, EarlyView.
This nationwide study of 960 hiatal hernia surgeries in Japan found that patients with Type I hernia had distinct characteristics and more favorable surgical outcomes compared to Types II–IV. Postoperative dysphagia was significantly associated with Types II–IV, preoperative dysphagia, and esophageal strictures, highlighting the need for careful ...
Soji Ozawa, Nobuo Omura, Kazuo Koyanagi, Junya Oguma, Akihito Kazuno, Yuko Kitagawa, Yoshihiro Kakeji, Yasushi Toh, Hisahiro Matsubara   +8 more
wiley   +1 more source

A bidirectional Mendelian randomization study integrating genome-wide association studies, expression quantitative trait locus, and methylation quantitative trait locus data revealed causal relationship between heavy cigarette dependence and Barrett’s esophagus

SAGE Open Medicine
Background: The association between smoking dependence and the risk of developing Barrett’s esophagus remains unclear. This study aimed to investigate whether a causal relationship exists between smoking dependence and Barrett’s esophagus, using ...
Zhou An, Meichun Zeng, Xianhua Wang
doaj   +1 more source