Results 101 to 110 of about 1,829,399 (343)
FEBS Open Bio, EarlyView.This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel +4 more
wiley +1 more source
Beilstein Journal of Nanotechnology, 2015 We investigate the effect of the thickness of the silicon nitride (SiNx) diffusion barrier on the structural and photocatalytic efficiency of TiO2 films obtained with different processes.
Mohamed Nawfal Ghazzal +3 more
doaj +1 more source
Calculations of widths in the problem of decay by proton emission [PDF]
, 2010 We develop a new fully quantum method for determination of widths for nuclear decay by proton emission where multiple internal reflections of wave packet describing tunneling process inside proton--nucleus radial barrier are taken into account.
Belchikov, Sergei V. +1 more
core
The Barrier Method: A Technique for Calculating Very Long Transition Times
, 2010 In many dynamical systems there is a large separation of time scales between typical events and "rare" events which can be the cases of interest.
Bartlett M. +6 more
core +1 more source
Implementing a Peer-Led, Low-Barrier Opioid Treatment Clinic in Longueuil Using a Photovoice Method [PDF]
, 2023 Andrée-Anne Paré-Plante +4 more
openalex +1 more source
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum
FEBS Open Bio, EarlyView.Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik +6 more
wiley +1 more source
Proposed method for estimating the costs of safety barrier life cycle
MATEC Web of Conferences, 2018 Today barrier types are frequently selected for their price with little regard for the total costs the structure will incur over its lifetime. One of the basic tools designed to manage road infrastructure is the life cycle cost method (LCC, Life cycle ...
Jamroz Kazimierz +3 more
doaj +1 more source
Nanomaterials, 2018 The SiOx barrier nanocoatings have been prepared on selected polymer matrices to increase their resistance against permeation of toxic substances. The aim has been to find out whether the method of vacuum plasma deposition of SiOx barrier nanocoatings on
Radek Prikryl +5 more
doaj +1 more source
Intercompartmental communication in senescence
FEBS Open Bio, EarlyView.Senescent cells experience structural changes in the plasma membrane, endoplasmic reticulum, mitochondria, lysosomes, nucleus, and cytoskeleton. These alterations disrupt crosstalk among cellular compartments, impairing vesicular trafficking, contact sites, and molecular flow.
Krystyna Mazan‐Mamczarz +3 more
wiley +1 more source