Results 31 to 40 of about 704,523 (264)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Verification of Approximate Initial-State Opacity for Control Systems via Neural Augmented Barrier Certificates

open access: yesMathematics, 2022
In this paper, we propose an augmented barrier certificate-based method for formally verifying the approximate initial-state opacity property of discrete time control systems.
Shengpu Wang   +3 more
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Quantitative PET imaging and modeling of molecular blood-brain barrier permeability

open access: yesNature Communications
Neuroimaging of blood-brain barrier permeability has been instrumental in identifying its broad involvement in neurological and systemic diseases. However, current methods evaluate the blood-brain barrier mainly as a structural barrier. Here we developed
Kevin J. Chung   +12 more
doaj   +1 more source

DETERMINING THE VALUE OF DOUBLE BARRIER OPTION USING STANDARD MONTE CARLO, ANTITHETIC VARIATE, AND CONTROL VARIATE METHODS

open access: yesBarekeng, 2023
In this paper, we applied the standard Monte Carlo, antithetic variate, and control variates methods to value the double barrier knock-in option price.
Romaito Br Silalahi   +2 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Determination of the Very High Barriers to Conformational Processes by the Neat Racemization Technique. Part 1: Barriers to Ring Inversion in Dibenzo [a,c] Dinaphtho [2,3-e; 2,3-g] Cyclooctatetraene and Hindered Rotation in 2,2'-Dimethyl Binaphthyl [PDF]

open access: yesIranian Journal of Chemistry & Chemical Engineering, 1996
A method is described by which it is possible to determine the high barrier to ring inversion and hindered rotation by neat racemization of optically active compounds when the racemization is caused by ring inversion or hindered rotation.
Parviz Rashidi Ranjbar   +3 more
doaj  

Efficient BEM-Based Algorithm for Pricing Floating Strike Asian Barrier Options (with MATLAB® Code)

open access: yesAxioms, 2018
This paper aims to illustrate how SABO (Semi-Analytical method for Barrier Option pricing) is easily applicable for pricing floating strike Asian barrier options with a continuous geometric average.
Alessandra Aimi   +2 more
doaj   +1 more source

A Practical Method for Controlling the Asymmetric Mode of Atmospheric Dielectric Barrier Discharges

open access: yesApplied Sciences, 2020
Atmospheric pressure dielectric barrier discharges (DBDs) have been applied in a very broad range of industries due to their outstanding advantages. However, different discharge modes can influence the stability of atmospheric DBDs, such as the density ...
Ling Luo   +4 more
doaj   +1 more source

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