Results 41 to 50 of about 316,083 (102)

The E3 ubiquitin ligase, RNF219, suppresses CNOT6L expression to exhibit antiproliferative activity

FEBS Open Bio, Volume 15, Issue 11, Page 1874-1885, November 2025.
We identified RNF219 as a CCR4‐NOT complex‐interacting E3 ubiquitin ligase that targets the CCR4‐NOT subunit CNOT6L for ubiquitination. RNF219 directly binds to the DUF3819 domain of CNOT1 through its putative α‐helix spanning amino acids 521–542. Our findings also suggest that antiproliferative activity of RNF219 is at least partially mediated by ...
Shou Soeda, Melissa Montrose, Akinori Takahashi, Risa Ishida, Sandrine Burriel, Nao Ohmine, Tohru Natsume, Shungo Adachi, Minsoo Kim, Tadashi Yamamoto   +9 more
wiley   +1 more source

3D Microstructural Characterization of Human Deep Fascia Using Optical Projection Tomography, Digital Light Sheet Microscopy, and Magnetic Resonance Microscopy

Microscopy Research and Technique, Volume 88, Issue 11, Page 3037-3049, November 2025.
The figure presents the trilaminar organization of the human deep fascia, composed of a thick, collagen‐rich intermediate layer flanked by thinner superficial and deep layers with loose connective tissue. ABSTRACT Traditional histological methods provide limited insights into the complex 3D microstructure of fascia and its relationship to disease. This
Chiedozie Kenneth Ugwoke, Barbora Radochová, Jiří Janáček, Igor Serša, Patrik Ganc, Erika Cvetko, Nejc Umek   +6 more
wiley   +1 more source

Dopamine dependency of oscillations between subthalamic nucleus and pallidum in Parkinson's disease [PDF]

, 2001
The extent of synchronization within and between the nuclei of the basal ganglia is unknown in Parkinson's disease. The question is an important one because synchronization will increase postsynaptic efficacy at subsequent projection targets.
Peter Brown, Vincenzo Di Lazzaro, Oliviero, A, Insola, A, Brown, Peter, Antonio Oliviero, Di Lazzaro, V, Mazzone, P, Brown, P, Pietro Tonali, Tonali, P, Paolo Mazzone, Angelo Insola   +12 more
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Abstracts

Molecular Oncology, Volume 20, Issue S1, Page 1-692, August 2026.
Abstracts submitted to the ‘EACR 2026 Congress: Innovative Cancer Science’, from 08–11 June 2026 and accepted by the Congress Organising Committee are published in this Supplement of Molecular Oncology, an affiliated journal of the European Association for Cancer Research (EACR).
wiley   +1 more source

Modelling the effects of deep brain stimulation in the pedunculopontine tegmental nucleus in Parkinson’s disease [PDF]

, 2014
Based on the belief that it is a locomotor control structure, the pedunculopontine tegmental nucleus (PPTg) has been considered a potential target for deep brain stimulation (DBS) for Parkinson’s disease (PD) patients with symptoms refractory to ...
Gut, Nadine Katrin
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Morphological evidence for enhanced kisspeptin and neurokinin B signaling in the infundibular nucleus of the aging man. [PDF]

, 2012
Peptidergic neurons synthesizing kisspeptin (KP) and neurokinin B (NKB) in the hypothalamic infundibular nucleus have been implicated in negative sex steroid feedback to GnRH neurons. In laboratory rodents, testosterone decreases KP and NKB expression in
Herczeg, László, Sipos, Máté T., Molnár, Csilla S., Vida, Barbara, Borsay, Beáta Á., Dhillo, Waljit S., Liposits, Zsolt, Hrabovszky, Erik, Rácz, Kálmán, Bloom, Stephen R., Ghatei, Mohammad A., Ciofi, Philippe   +11 more
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RECOVER Guidelines: Newborn Resuscitation in Dogs and Cats. Evidence and Knowledge Gap Analysis With Treatment Recommendations

Journal of Veterinary Emergency and Critical Care, Volume 35, Issue S1, Page 3-59, August 2025.
ABSTRACT Objective To systematically review the evidence on, to devise clinical recommendations for, and to identify critical knowledge gaps in resuscitation of newborn puppies and kittens. Design Standardized, systematic evaluation of literature pertinent to newborn resuscitation following Grading of Recommendations, Assessment, Development, and ...
Manuel Boller, Jamie M. Burkitt‐Creedon, Christopher G. Byers, Daniel J. Fletcher, Kate S. Farrell, Autumn P. Davidson, Suzanne Fricke, Giovanna Bassu, Sophie A. Grundy, Cheryl Lopate, Maria C. Veronesi, the RECOVER Newborn Resuscitation Domain Evidence Evaluators, Barbara Ambros, Samantha M. Aumann, Amy L. Bell, Steven T. Berkowitz, Erin M. Binagia, Jennifer L. Bornkamp, Luis Bosch Lozano, Leslie J. Carter, Rosalind S. Chow, Kimberly N. Claus, Lillian Cousto, Ian M. DeStefano, Jillian DiFazio, Neus Elias Santo‐Domingo, Rebecca S. Flores, Emily F. Floyd, Christine Fox, Suzanne Fricke, Anthony L. Gonzales, Jennifer M. Good, Eduardo Gutierrez‐Blanco, Jenica L. Haraschak, Amanda J. Hilliard, Katherine J. Howie, Kristen M. Hutchinson, Matthias Kohlhauer, Pen‐Ting Liao, Kristen Marshall, Carolyn McKune, Amelia S. Munsterman, Katherine J. Nash, Christopher L. Norkus, Tania E. Perez Jimenez, Carlos Pizarro Del Valle, Molly A. Racette, Andrea Sanchez, Eric L. Schroeder, Deborah C. Silverstein, M. Ryan Smith, Susanna Solbak, Erin A. Spencer, Tamara M. Swor, Erica W. Tinson, Renaud Tissier, Chia T. Tseng, Yu Ueda, Kelley M. Varner, Meghan E. Vaught, Linda K. Weatherton, Helen E. Wilson, Eunice L. Yuh, Kristin M. Zersen   +63 more
wiley   +1 more source

Mouse nuclear myosin I knock-out shows interchangeability and redundancy of myosin isoforms in the cell nucleus. [PDF]

, 2013
Nuclear myosin I (NM1) is a nuclear isoform of the well-known "cytoplasmic" Myosin 1c protein (Myo1c). Located on the 11(th) chromosome in mice, NM1 results from an alternative start of transcription of the Myo1c gene adding an extra 16 amino acids at ...
Dzijak, Rastislav, Eckhard Wolf, Oliver Eickelberg, Fuchs Helmut, Alexander Bohla, Schmidt, Volker, Rülicke, T., Hrabě de Angelis, M., Rohožková, Jana, Alžběta Kalendová, Martin Hrabě de Angelis, Schmidt Volker, Dzijak, R., Kalendová, Alžběta, Rathkolb, Birgit, Hozák, Pavel, Dzijak Rastislav, Hans, Wolfgang, Ali Önder Yildirim, Rathkolb, B., Venit, Tomáš, Wolf Eckhard, Hans Wolfgang, Yildirim Ali Önder, Fuchs, H., Hozák Pavel, Bohla Alexander, Stoeger Tobias, Gailus-Durner, Valérie, Jana Rohožková, Hrabé de Angelis, Martin, Kahle-Stephan, M., Valérie Gailus-Durner, Wolf, E., Stoeger, Tobias, Thomas Rülicke, Gailus-Durner, V., Volker Schmidt, Kahle Michal, Helmut Fuchs, Kahle, Michal, Eickelberg, O., Kalendova, A., Venit Tomáš, Eickelberg Oliver, Bohla, A., Rastislav Dzijak, Michal Kahle, Rohožková Jana, Yildirim, A.Ö., Venit, T., Eickelberg, Oliver, Stöger, T., Wolfgang Hans, Rülicke Thomas, Hans, W., Rohozkova, J., Rathkolb Birgit, Bohla, Alexander, Birgit Rathkolb, Rülicke, Thomas, Tobias Stoeger, Tomáš Venit, Fuchs, Helmut, de Angelis Martin Hrabě, Schmidt, V., Yildirim, Ali Önder, Gailus-Durner Valérie, Wolf, Eckhard, Hozak, P., Kalendová Alžběta, Pavel Hozák, Venit, T. ; Dzijak, R. ; Kalendova, A. ; Kahle, M. ; Rohozkova, J. ; Schmidt, V. ; Rülicke, T. ; Rathkolb, B. ; Hans, W. ; Bohla, A. ; Eickelberg, O. ; Stöger, T. ; Wolf, E. ; Yildirim, A.Ö. ; Gailus-Durner, V. ; Fuchs, H. ; Hrabé de Angelis, M. ; Hozak, P.   +72 more
core   +2 more sources

Linking actions to outcomes : the role of the posterior pedunculopontine tegmental nucleus in instrumental learning [PDF]

, 2012
Located in the mesopontine tegmentum, the pedunculopontine tegmental nucleus (PPTg) is comprised principally of glutamatergic, cholinergic and GABAergic neurons.
MacLaren, Duncan A. A.
core   +2 more sources

Connections of Barrington's nucleus to the sympathetic nervous system in rats.

, 2000
Barrington's nucleus (BN) has been considered a pontine center related exclusively to the control of pelvic parasympathetic activity. The present study demonstrates an anatomical linkage between BN and autonomic outflow to visceral targets innervated ...
Sved, A F, Card, J P, Cano, G, Rinaman, Linda   +3 more
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