Results 21 to 30 of about 946 (107)

Early adversity and the comorbidity between metabolic disease and psychopathology

open access: yesThe Journal of Physiology, Volume 604, Issue 11, Page 4338-4377, 1 June 2026.
Abstract figure legend Hierarchical diagram representing the interplay between the genetic background and early life adversities and its effect on multiple physiological processes that ultimately impact on the risk for the comorbdity between psychopathology and cardiometabolic disorders.
Ameyalli Gómez‐Ilescas   +1 more
wiley   +1 more source

Carrier screening in the reproductive setting—Are there medical implications for the heterozygote?—A guide for clinicians

open access: yesPregnancy, Volume 2, Issue 3, May 2026.
Abstract Carrier screening for genetic conditions performed preconception or during pregnancy allows identification of fetal risk for inherited autosomal recessive and X‐linked conditions. The goal is to identify at‐risk patients/couples and offer them reproductive options such as preimplantation genetic diagnosis, prenatal testing, or targeted newborn
Emily B. Rosenfeld   +5 more
wiley   +1 more source

Novel drugs approved by the EMA, the FDA and the MHRA in 2025: A year in review

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 9, Page 1779-1813, May 2026.
Abstract In the 2025 novel drug mini‐review, one can take a full measure of the ingenuity that underlies current drug design and development, despite the year's smaller harvest (46 novel drugs) compared to 2024 (53) and 2023 (70). 54% of the novel drugs are first‐in‐class (FIC).
Andreas Papapetropoulos   +16 more
wiley   +1 more source

Vector‐borne diseases‐knowledge maps

open access: yesEFSA Journal, Volume 24, Issue 5, May 2026.
Abstract This scientific report provides a structured overview of the main characteristics of 25 selected vector‐borne diseases (VBDs) of potential relevance for the EU, including 12 diseases listed under the Animal Health Law (AHL) and 13 non‐listed diseases.
European Food Safety Authority (EFSA)   +7 more
wiley   +1 more source

Gendering the Menstrual Cycle in Behavioral Neuroendocrinology

open access: yesAmerican Journal of Human Biology, Volume 38, Issue 4, April 2026.
ABSTRACT The menstrual cycle is increasingly described as a “vital sign of the female body,” with the literature suggesting cycle‐related brain and behavioral changes. With growing interest in the effects that the menstrual cycle has on the brain, body and mind, characterizing what constitutes healthy cycle‐related change has become a central goal of ...
Annie Duchesne   +2 more
wiley   +1 more source

The Timing and Experience of Menopause among British Pakistani Women in Bradford and Leeds, West Yorkshire, UK [PDF]

open access: yes, 2009
Previous studies have shown considerable differences at both the population and individual levels in the timing of menopause and the experience of physical and emotional changes related to menopause (generally called symptoms).
Blell, Mwenza Thandiwe   +1 more
core  

Expert‐Designed Fact Sheets and AI‐Based Analysis of Patient Symptoms to Combat Diagnostic Delays in Inherited Metabolic Diseases

open access: yesJournal of Inherited Metabolic Disease, Volume 49, Issue 2, March 2026.
ABSTRACT The importance of early diagnosis of inherited metabolic diseases (IMDs) is well known, as it allows early intervention to prevent or reduce complications and improve prognosis, since many of these disorders are treatable. However, diagnosis can still be delayed, and many patients remain undiagnosed. Reducing diagnosis delays is a primary goal
Aline Cano   +108 more
wiley   +1 more source

The development of a quality of life instrument for osteoarthritis [PDF]

open access: yes, 2007
Osteoarthritis (OA) is a common condition and a leading cause of pain and disability. The aim of this thesis was to explore issues associated with living with OA, develop an OA specific quality of life instrument and explore the physical and psychosocial
Keenan, Anne-Maree
core  

Severity of Depressive Symptoms by Perceived Stress and Gut Microbiota Composition: A Sex‐Stratified Bayesian Approach in a Non‐Clinical Sample

open access: yesStress and Health, Volume 42, Issue 1, February 2026.
ABSTRACT Gut dysbiosis, an imbalance in gut microbiota, is increasingly linked to depression through the microbiota‐gut‐brain axis. Stress is an important risk factor for both gut dysbiosis and depression. Despite evidence of altered gut microbiota composition in patients with depression, little is known about how stress and specific gut microbiota ...
Sylvia De Napoli   +7 more
wiley   +1 more source

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