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Distribution of Basal Cell Carcinoma and Squamous Cell Carcinoma by Facial Esthetic Unit [PDF]

open access: yesArchives of Plastic Surgery, 2013
Background  The most common cutaneous malignant masses are basal cell carcinoma (BCC)and squamous cell carcinoma. The predominant site of a malignant mass is the face, whichhas many opportunities to be exposed to ultraviolet radiation.
Jung Hun Choi   +4 more
doaj  

Aspiration metastases from basal cell carcinoma [PDF]

open access: bronze, 1958
John W. Pickren, Alfred D. Katz
openalex   +1 more source

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

open access: yesFEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu   +17 more
wiley   +1 more source

Goodbye flat lymphoma biology

open access: yesFEBS Letters, EarlyView.
Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria   +3 more
wiley   +1 more source

Forehead reduction: option for reconstructing forehead defects [PDF]

open access: yesSurgical & Cosmetic Dermatology
Three-dimensional facial analysis is the basis for planning appropriate treatment. We evaluated the face in thirds. The distance from the hairline to the glabella, from the glabella to the subnasale and from the subnasale to the menton must be equal ...
Vitoria Azulay   +4 more
doaj   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

open access: yesFEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan   +2 more
wiley   +1 more source

Histomorphological evaluation of skin lesions at the Kadapa Government Medical College teaching institute: A two-year study [PDF]

open access: yesJournal of Clinical and Basic Research
Background: The prevalence of skin diseases varies geographically due to factors, such as etiology, environment, genetics, and lifestyle. The current study aimed to determine the incidence and distribution of skin disorders and to provide a description ...
Velpula Nagesh Kumar   +3 more
doaj  

The anabolic steroid stanozolol is a potent inhibitor of human MutT homolog 1

open access: yesFEBS Letters, EarlyView.
MutT homolog 1 (MTH1) is a member of the NUDIX superfamily of enzymes and is an anticancer drug target. We show that stanozolol (Stz), an anabolic steroid, is an unexpected nanomolar inhibitor of MTH1. The X‐ray crystal structure of the human MTH1–Stz complex reveals a unique binding scaffold that could be utilized for future inhibitor development ...
Emma Scaletti Hutchinson   +7 more
wiley   +1 more source

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