Results 101 to 110 of about 980,683 (314)

CXCR3/Ligands Are Significantly Involved in the Tumorigenesis of Basal Cell Carcinomas [PDF]

, 2010
Blanche K.K. Lo, Mei Yu, David Zloty, Bryce J. Cowan, Jerry Shapiro, Kevin J. McElwee   +5 more
openalex   +1 more source

Targeting EZH2 reverses thyroid cell dedifferentiation and enhances iodide uptake in anaplastic thyroid cancer

FEBS Letters, EarlyView.
Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello, Marcella Maringolo Cristovão, Guilherme Henrique, Vinicius Gonçalves Rodrigues, Caroline Serrano‐Nascimento, Edna Teruko Kimura, Cesar Seigi Fuziwara   +6 more
wiley   +1 more source

Benzethonium Chloride: A Novel Anticancer Agent Identified by Using a Cell-Based Small-Molecule Screen [PDF]

, 2006
Kenneth W. Yip, Xinliang Mao, P Au, David W. Hedley, Sue Chow, Shadi Dalili, Joseph D. Mocanu, Carlo Bastianutto, Aaron D. Schimmer, Fei‐Fei Liu   +9 more
openalex   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Basal cell carcinoma

BMJ, 2003
C S M, Wong, R C, Strange, J T, Lear
openaire   +3 more sources

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

Comparative Study of p53 and Ki-67 Expression in Different Histologic Variants of Basal Cell Carcinoma

پزشکی بالینی ابن سینا, 2012
Introduction & Objective: Basal cell carcinoma is the most common malignant tumor in humans. The role of ultraviolet radiation is well known in pathogenesis of BCC.
Alireza Monsef, Akram Ansar, Sahar Behnoud, Hamidreza Ghidimipour, Seyyes Mostafa Ghasemzadeh   +4 more
doaj  

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

FEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang, Naoki Sunagawa, Toma Kashima, Kiyohiko Igarashi, Akimasa Miyanaga, Shinya Fushinobu   +5 more
wiley   +1 more source

Prevalence of skin cancers in kidney transplant recipients - one-center experience

Frontiers in Oncology
IntroductionNon-melanoma skin cancers (NMSCs) are the most common neoplasms that occur in solid organ transplant recipients (SOTRs). Squamous cell carcinoma (SCC) and basal cell carcinoma (BCC) make up over 90% of skin cancers in SOTRs.
Fabian Kosko, Alicja Dębska-Ślizień, Beata Imko-Walczuk, Maria Luiza Piesiaków, Bogdan Biedunkiewicz, Barbara Bułło-Piontecka, Beata Bzoma, Andrzej Chamienia, Justyna Gołębiewska, Joanna Konopa, Ewa Król, Tomasz Liberek, Monika Lichodziejewska-Niemierko, Sławomir Lizakowski, Przemysław Rutkowski, Agnieszka Tarasewicz, Marcin Wczysla, Zbigniew Heleniak   +17 more
doaj   +1 more source