Results 131 to 140 of about 939,843 (294)

Comparative Study of p53 and Ki-67 Expression in Different Histologic Variants of Basal Cell Carcinoma

open access: yesپزشکی بالینی ابن سینا, 2012
Introduction & Objective: Basal cell carcinoma is the most common malignant tumor in humans. The role of ultraviolet radiation is well known in pathogenesis of BCC.
Alireza Monsef   +4 more
doaj  

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan   +10 more
wiley   +1 more source

Elucidating prognostic significance of purine metabolism in colorectal cancer through integrating data from transcriptomic, immunohistochemical, and single‐cell RNA sequencing analysis

open access: yesMolecular Oncology, EarlyView.
Low expression of five purine metabolism‐related genes (ADSL, APRT, ADCY3, NME3, NME6) was correlated with poor survival in colorectal cancer. Immunohistochemistry analysis showed that low NME3 (early stage) and low ADSL/NME6 (late stage) levels were associated with high risk.
Sungyeon Kim   +8 more
wiley   +1 more source

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

open access: yesMolecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka   +10 more
wiley   +1 more source

BASAL CELL CARCINOMA OF THE ANUS

open access: green, 1949
Bruce D. Lott, Carter M. Alexander
openalex   +2 more sources

Citrulline-containing basal cell carcinomas. Differentiation toward hair structures with induction of dermal hair papillae [PDF]

open access: bronze, 1968
Elizabeth J. Holmes   +2 more
openalex   +1 more source

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