EXPERIMENTALLY INDUCED CHANGES IN THE BASE COMPOSITION OF THE RIBONUCLEIC ACIDS OF ISOLATED NERVE CELLS AND THEIR OLIGODENDROGLIAL CELLS [PDF]
, 1961 E. Egyházi, Holger Hydén
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A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source
Smoothened variants explain the majority of drug resistance in basal cell carcinoma.
Cancer Cell, 2015 Scott X. Atwood +11 more
semanticscholar +1 more source
Clinical Features and Outcomes of Locally Advanced and Metastatic Basal Cell Carcinoma. [PDF]
Acta Derm VenereolZwanenburg AAJH +5 more
europepmc +1 more source
Citrulline-containing basal cell carcinomas. Differentiation toward hair structures with induction of dermal hair papillae [PDF]
, 1968 Elizabeth J. Holmes +2 more
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Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma
Molecular Oncology, EarlyView.The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias +12 more
wiley +1 more source
A Case of Basal Cell Carcinoma Arising in Congenital Triangular Alopecia. [PDF]
CureusBai A, Namazian S, Elliott E.
europepmc +1 more source
The Syndrome of Jaw Cysts, Basal Cell Tumours and Skeletal Anomalies [PDF]
, 1964 R.A. Cawson, Gemma Kerr
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Molecular Oncology, EarlyView.Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley +1 more source