Results 41 to 50 of about 964,707 (319)

Periungual basal cell carcinoma [PDF]

open access: yesAnais Brasileiros de Dermatologia, 2018
Periungual basal cell carcinoma is rare and needs to be differentiated from other common diseases that affect this region. Several factors are associated with the development of this tumor, and sun damage seems to play an important role in its pathogenesis.
Tavares, Laura Loures   +3 more
openaire   +5 more sources

The dual nature of TDC – bridging dendritic and T cells in immunity

open access: yesFEBS Letters, EarlyView.
TDC are hematopoietic cells combining dendritic and T cell features. They reach secondary lymphoid organs (SLOs) and peripheral organs (liver and lungs) after FLT3‐dependent development in the bone marrow and maturation in the thymus. TDC are activated and enriched in SLOs upon viral infection, suggesting that they might play unique immune roles, since
Maria Nelli, Mirela Kuka
wiley   +1 more source

A Macroscopic Mathematical Model For Cell Migration Assays Using A Real-Time Cell Analysis [PDF]

open access: yesPLoS ONE 11(9): e0162553, 2016, 2016
Experiments of cell migration and chemotaxis assays have been classically performed in the so-called Boyden Chambers. A recent technology, xCELLigence Real Time Cell Analysis, is now allowing to monitor the cell migration in real time. This technology measures impedance changes caused by the gradual increase of electrode surface occupation by cells ...
arxiv   +1 more source

Leveraging current insights on IL‐10‐producing dendritic cells for developing effective immunotherapeutic approaches

open access: yesFEBS Letters, EarlyView.
In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali   +3 more
wiley   +1 more source

Advancement and Potential Applications of Epididymal Organoids

open access: yesBiomolecules
The epididymis, a key reproductive organ, is crucial for sperm concentration, maturation, and storage. Despite a comprehensive understanding of many of its functions, several aspects of the complex processes within the epididymis remain obscure ...
Junyu Nie, Hao Chen, Xiuling Zhao
doaj   +1 more source

Polarized Entry of Human Parechoviruses in the Airway Epithelium

open access: yesFrontiers in Cellular and Infection Microbiology, 2018
Human parechoviruses (HPeVs), a poorly studied genus within the Picornaviridae family, are classified into 19 genotypes of which HPeV1 and HPeV3 are the most often detected.
Eveliina Karelehto   +10 more
doaj   +1 more source

Intracellular coupling modulates biflagellar synchrony [PDF]

open access: yesarXiv, 2020
Beating flagella exhibit a variety of synchronization modes. This synchrony has long been attributed to hydrodynamic coupling between the flagella. However, recent work with flagellated algae indicates that a mechanism internal to the cell, through the contractile fibres connecting the flagella basal bodies, must be at play to actively modulate ...
arxiv  

A Mechanical Instability in Planar Epithelial Monolayers Leads to Cell Extrusion [PDF]

open access: yes, 2018
In cell extrusion, a cell embedded in an epithelial monolayer loses its apical or basal surface and is subsequently squeezed out of the monolayer by neighboring cells. Cell extrusions occur during apoptosis, epithelial-mesenchymal transition, or pre-cancerous cell invasion.
arxiv   +1 more source

A basal contribution from p-modes to the Alfvénic wave flux in the Sun's corona [PDF]

open access: yesNature Astronomy 2019, 2019
Many cool stars possess complex magnetic fields [1] that are considered to undertake a central role in the structuring and energising of their atmospheres [2]. Alfv\'enic waves are thought to make a critical contribution to energy transfer along these magnetic fields, with the potential to heat plasma and accelerate stellar winds [3] [4] [5].
arxiv   +1 more source

FoxO1 signaling in B cell malignancies and its therapeutic targeting

open access: yesFEBS Letters, EarlyView.
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac   +3 more
wiley   +1 more source

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