AGE-modified basement membrane cooperates with Endo180 to promote epithelial cell invasiveness and decrease prostate cancer survival [PDF]
, 2014 Biomechanical strain imposed by age-related thickening of the basal lamina and augmented tissue stiffness in the prostate gland coincides with increased cancer risk. Here we hypothesized that the structural alterations in the basal lamina associated with
Breit, Claudia +14 more
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Advancement and Potential Applications of Epididymal Organoids
BiomoleculesThe epididymis, a key reproductive organ, is crucial for sperm concentration, maturation, and storage. Despite a comprehensive understanding of many of its functions, several aspects of the complex processes within the epididymis remain obscure ...
Junyu Nie, Hao Chen, Xiuling Zhao
doaj +1 more source
Population Ecology, EarlyView.Bear management changes management actions according to the horizontal axis of the population size and the vertical axis of the number of nuisance bears. Aiming for the target population size of Ntar, Actions I and II protect the bears, and Action IV reduces the population.
Hiroyuki Matsuda +5 more
wiley +1 more source
Third-codon transversion rate-based _Nymphaea_ basal angiosperm phylogeny -- concordance with developmental evidence [PDF]
, 2007 Flowering plants (angiosperms) appeared on Earth rather suddenly approximately 130 million years ago and underwent a massive expansion in the subsequent 10-12 million years.
(Max) Zong-Ming Cheng +4 more
core +2 more sources
NowotworyThe paper presents recommendations concerning the surveillance of patients after the treatment of squamous-cell carcinoma (SCC), basal-cell carcinoma (BCC) and Merkel-cell carcinoma (MCC) based on the current European and American recommendations.
Wojciech M. Wysocki +12 more
doaj +1 more source
FoxO1 signaling in B cell malignancies and its therapeutic targeting
FEBS Letters, EarlyView.FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac +3 more
wiley +1 more source
Control of Arabidopsis apical-basal embryo polarity by antagonistic transcription factors. [PDF]
, 2010 Plants, similarly to animals, form polarized axes during embryogenesis on which cell differentiation and organ patterning programs are orchestrated. During Arabidopsis embryogenesis, establishment of the shoot and root stem cell populations occurs at ...
Long, Jeff A, Smith, Zachery R
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Body site locations of basal cell carcinoma, squamous cell carcinoma and actinic keratosis in patients referred to the Waikato District Health Board teledermoscopy clinic [PDF]
Journal of Primary Health Care, 2022 IntroductionBasal cell carcinoma (BCC), squamous cell carcinoma (SCC) and actinic keratosis (AK) are usually located on sun-exposed areas of the body.
Amanda Oakley +3 more
doaj
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
FEBS Letters, EarlyView.This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
Growth Hormone (GH)-Releasing Peptide Stimulation of GH Release from Human Somatotroph Adenoma Cells: Interaction with GH-Releasing Hormone, Thyrotropin- Releasing Hormone, and Octreotide. [PDF]
, 1994 The synthetic hexapeptide GH-releasing peptide (GHRP; His-D-Trp-Ala-Trp-D-Phe-Lys-NH2) specifically stimulates GH secretion in humans in vivo and in animals in vitro and in vivo via a still unknown receptor and mechanism.
Brockmeier, S. +7 more
core +1 more source