Results 111 to 120 of about 238,188 (312)

Basal Cell Carcinoma and Rhinophyma: A Novel Treatment Option [PDF]

, 2011
Parker A. Velargo, Merry Sebelik
openalex   +1 more source

Pigmented basal cell carcinoma [PDF]

Indian Journal of Surgery, 2009
John J S, Martis, Rohan, Gatty, K V, Rajeshwara, Dayanand, Jairaj, Sunil, Sudharshan   +4 more
openaire   +2 more sources

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

PD12-04 RISK-BASED SURVEILLANCE AFTER SURGICAL TREATMENT OF RENAL CELL CARCINOMA [PDF]

, 2018
Paolo Capogrosso, Alessandro Larcher, Daniel D. Sjoberg, Emily Vertosick, Francesco Cianflone, Fabio Muttin, Paolo Dell’Oglio, Andrea Salonia, Andrew J. Vickers, Francesco Montorsi, Roberto Bertini, Umberto Capitanio   +11 more
openalex   +1 more source

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

Molecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek, Jenny Sprooten, Abhishek D. Garg   +2 more
wiley   +1 more source

Actin dynamics controlled by IqgC, a RasGAP at the crossroads between the IQGAP and fungal GAP1 families

FEBS Open Bio, EarlyView.
IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić, Darija Putar, Lucija Mijanović, Igor Weber   +3 more
wiley   +1 more source

Basal-to-inflammatory transition and tumor resistance via crosstalk with a pro-inflammatory stromal niche

Nature Communications
Cancer-associated inflammation is a double-edged sword possessing both pro- and anti-tumor properties through ill-defined tumor-immune dynamics. While we previously identified a carcinoma tumor-intrinsic resistance pathway, basal-to-squamous cell ...
Nancy Yanzhe Li, Weiruo Zhang, Daniel Haensel, Anna R. Jussila, Cory Pan, Sadhana Gaddam, Sylvia K. Plevritis, Anthony E. Oro   +7 more
doaj   +1 more source

Activation of the basal cell carcinoma pathway in a patient with CNS HGNET-BCOR diagnosis: consequences for personalized targeted therapy

, 2016
Claudia Paret, Johanna Theruvath, Alexandra Russo, Bettina Kron, Khalifa El Malki, Nadine Lehmann, Arthur Wingerter, Marie A. Neu, Aslihan Gerhold‐Ay, Wolfgang Wagner, Clemens Sommer, Torsten Pietsch, Larissa Seidmann, Jörg Faber   +13 more
openalex   +2 more sources

Epidemiological and clinicopathological analysis of basal cell carcinoma in Egyptian population: a 5-year retrospective multicenter study [PDF]

, 2022
Mohamed El‐Khalawany, Hussein Mohamed Hassab-El-Naby, Ahmed Mustafa Mousa, Ahmed Sameh, Mahmoud A. Rageh, Rasha M. Genedy, Aya Magdy Hosny, Marwa A. Aboelmagd, Mohammed Abu El‐Hamd   +8 more
openalex   +1 more source

Lactoferrin treatment activates acetylcholinesterase, decreasing acetylcholine levels in non‐small cell lung cancer (NSCLC) cell culture supernatants, inhibiting cell survival

FEBS Open Bio, EarlyView.
Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel, Caroline Wozniak, Aya Sabri, Ben Haddad, Brooke Lopo, Alvaro Cobos, Sarah Sarofim, Jeffrey Guthrie, Deborah Heyl, Hedeel Guy Evans   +9 more
wiley   +1 more source