Results 121 to 130 of about 2,712,964 (379)
Cutaneous basal cell carcinoma mimicking small cell carcinoma
Clinical Case Reports, 2019 Key Clinical Message Neuroendocrine differentiation seen in basal cell carcinomas (BCC) is not generally appreciated by oncologists and can introduce a component of confusion when diagnosing a tumor and developing a management plan.
Samara E. Pollock +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen +12 more
wiley +1 more source
The effect of socio-economic status on severity of periocular basal cell carcinoma at presentation [PDF]
, 2015 Purpose: To evaluate the influence of socio-economic factors on size of periocular basal cell carcinoma at presentation. Methods: All periocular basal cell carcinoma cases receiving treatment from the oculoplastics team in South Glasgow Hospitals NHS ...
Agarwal, Pankaj K. +4 more
core +1 more source
Giant basal cell carcinoma associated with vitiligo
Clinical Case Reports, 2019 We report a woman with two giant Basal cell carcinomas (BCCs) on the back, the largest with 12 cm in diameter, inside a vitiligo plaque. They were metatypical subtype BCC associated with a nodular subtype area.
Luiza Fiszon‐Cerqueira +5 more
doaj +1 more source
Management of high-risk and advanced basal cell carcinoma
Clinical and Translational Oncology, 2015 Despite that basal cell carcinoma (BCC) is curative in the vast majority of cases, some patients are at high risk of recurrence and, in a few patients, lesions can progress to a point unsuitable for local therapy and prognosis is quite poor.
Susana Puig, A. Berrocal
semanticscholar +1 more source
Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence
Molecular Oncology, EarlyView.The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova +18 more
wiley +1 more source
Molecular Oncology, EarlyView.This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu +12 more
wiley +1 more source
Biomarkers of basal cell carcinoma resistance to methyl-aminolevulinate photodynamic therapy [PDF]
, 2019 This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Gilaberte, Yolanda +6 more
core +4 more sources
DERMOSCOPIC DIAGNOSTIC CRITERIA IN DIFFERENT MORPHOLOGICAL TYPES OF BASALIOMA
Alʹmanah Kliničeskoj Mediciny, 2016 Background: Basal cell carcinoma of the skin (BCC, basalioma) is one of the most common malignant skin tumors. Dermoscopy is the most available today method of non-invasive diagnosis of skin tumors.
A. N. Khlebnikova, N. V. Novoselova
doaj +1 more source
Landscape of BRAF transcript variants in human cancer
Molecular Oncology, EarlyView.We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda +5 more
wiley +1 more source