Results 221 to 230 of about 382,033 (356)

Strategies to Improve the Lipophilicity of Hydrophilic Macromolecular Drugs

Advanced Healthcare Materials, EarlyView.
Hydrophilic macromolecular drugs can be successfully lipidized by covalent attachment of lipids, by hydrophobic ion pairing with negatively or positively charged surfactants, and by dry or wet reverse micelle formation. Lipophilicity enhancement of hydrophilic macromolecules has several benefits including stability and bioavailability improvement ...
Sera Lindner, Stefan Keim, Soheil Haddadzadegan, Odile Fernandez Romero, Katrin Zöller, Gabriel Stern, Ilaria Cesi, Krum Kafedjiiski, Andreas Bernkop‐Schnürch   +8 more
wiley   +1 more source

Clinical Features and Outcomes of Locally Advanced and Metastatic Basal Cell Carcinoma. [PDF]

Acta Derm Venereol
Zwanenburg AAJH, Van Houdt WJ, Schrijver AM, Schreuder WH, Wouters MWJM, Plasmeijer EI.   +5 more
europepmc   +1 more source

Table S1 from Dietary Fish and n-3 Polyunsaturated Fatty Acid Consumption, and Renal Cell Carcinoma Risk in Japan: The Japan Public Health Center-Based Prospective Study

Michiko Takahashi, Tomotaka Sobue, Ling Zha, Tetsuhisa Kitamura, Motoki Iwasaki, Manami Inoue, Taiki Yamaji, Shoichiro Tsugane, Norie Sawada   +8 more
openalex   +1 more source

Peptomer Linkers Enable Kinetic Control over Co‐Delivery of Multiple Chemotherapeutics

Advanced Healthcare Materials, EarlyView.
A key challenge in combinatorial chemotherapeutic drug delivery is independent control over release kinetics, especially with drugs of similar size and structure. Here, peptoid substitutions to proteolytically degradable peptides enabled the design of fast and slow‐releasing drug linkers.
Carolyn M. Watkins, Samuel L. Hallam, Mariah J. Austin, Adrianne M. Rosales   +3 more
wiley   +1 more source

Global basal cell carcinoma in 55+ population: 1990- 2021 burden、risk-factor trends and 2050 forecast. [PDF]

Front Oncol
Cai YX, Rong M.
europepmc   +1 more source

Additional file 1 of Molecular subtyping based on RYR2 correlates prognosis and tumor mutation burden in lung squamous cell carcinoma patients

Prithvi Singh, Asifa Khan, Mohammad Masood, Shivani Tyagi, Nitesh Shriwash, Bhupender Kumar, Pramod Katara, Mohammad Mahfuzul Haque, Ravins Dohare   +8 more
openalex   +1 more source

Temporal trends of the disease burden of renal cell carcinoma from 1992 to 2019 in the US: A population-based analysis [PDF]

Ruyan Chen, Tian Tang, Jianglong Han, Li Si, Wenmin Liu, Haiyu Deng, Tingting Jian, Zhenming Fu   +7 more
openalex   +1 more source

Delivery of Multifunctional Microspheres via Intravesical Instillation for Bladder Carcinoma: Therapeutic Potential and Mechanistic Insights

Advanced Healthcare Materials, EarlyView.
PCTM microspheres were successfully synthesized using microfluidic and click chemistry techniques.In Vivo and in vitro experiments have shown that PCTM microspheres have obvious targeting, adhesion, membrane penetration and anti‐tumor properties for bladder tumors.The antitumor mechanism of PCTM microspheres is to indirectly induce S‐stage blockage of ...
Zhaoxiang Lu, Wentie Yang, Youzhi Hong, Yusen Qiao, Chaozhao Liang   +4 more
wiley   +1 more source

A case of labyrinthine pattern basal cell carcinoma. [PDF]

An Bras Dermatol
Nakamura T, Yamamoto T.
europepmc   +1 more source

Characterization of Microplastics in Human Gastric Cancer and Control Tissues and Analysis of Associated Genetic Features

Advanced Healthcare Materials, EarlyView.
This study characterizes the presence of microplastics in human normal gastric, para‐tumor, and gastric tumor tissue and confirms the association between microplastic exposure and lymph node metastasis in gastric cancer. This study explores the transcriptomic changes induced by microplastic exposure, laying the foundation for further investigation into
Liqiao Chen, Jialin Li, Yan Wu, Han Bao, Xuesong Yang, Guoqing Lv, Ke Ji, Ji Zhang, Xiaojiang Wu, Kai Zhou, Jieli Xu, Jiatian Tang, Xiyuan Han, Anqiang Wang   +13 more
wiley   +1 more source