Results 61 to 70 of about 2,712,964 (379)

A Clinical Study of Basal Cell Carcinoma

Medical archives, 2019
Introduction: Basal cell carcinoma (BCC) is a non-melanocytic skin malignancy arising from basal cells of epidermis or follicular structures. Etiology of BCC is a multifactorial combination of genotype, phenotype, and environmental factors.
E. Kasumagić-Halilović, Mediha Hasic, Nermina Ovčina-Kurtović   +2 more
semanticscholar   +1 more source

Ocular manifestations in Gorlin-Goltz syndrome [PDF]

, 2019
Background: Gorlin-Goltz syndrome, also known as nevoid basal cell carcinoma syndrome, is a rare genetic disorder that is transmitted in an autosomal dominant manner with complete penetrance and variable expressivity.
Franzone, F., Giustini, S., Himmelblau, E., Iacovino, C., Lambiase, A., Mallone, F., Miraglia, E., Moramarco, A., Roberti, V.   +8 more
core   +1 more source

Update on Hedgehog Pathway Inhibitor Therapy for Patients with Basal Cell Naevus Syndrome or High-frequency Basal Cell Carcinoma

Acta Dermato-Venereologica, 2022
Some patients with basal cell carcinoma develop a large number of basal cell carcinomas during their lives. The most common underlying genetic disease that causes multiple basal cell carcinomas is basal cell naevus syndrome. Basal cell naevus syndrome is
Babette J.A. Verkouteren, Kelly A.E. Sinx, Marie G.H.C. Reinders, Maureen J.B. Aarts, Klara Mosterd   +4 more
doaj   +1 more source

Histological Review of Skin cancers in African Albinos: A 10-year Retrospective Review. [PDF]

, 2014
Skin cancer is rare among Africans and albinism is an established risk for skin cancer in this population. Ultraviolet radiation is highest at the equator and African albinos living close to the equator have the highest risk of developing skin cancers ...
A Yakubu, AN Okoro, Baraka Michael Chaula, DS Rigel, GA Alexander, Helmut Beltraminelli, HM Gloster Jr, J Higgenson, J Luande, JB Mabula, JG Kromberg, K Grønskov, KO Opara, PM Lund, Samson Kimaiyo Kiprono, SR McBride, T Brenn, TL Diepgen, TR Fears, TW Ridky   +19 more
core   +2 more sources

Long‐term efficacy and safety of sonidegib in patients with locally advanced and metastatic basal cell carcinoma: 30‐month analysis of the randomized phase 2 BOLT study

Journal of the European Academy of Dermatology and Venereology, 2017
Patients with locally advanced basal cell carcinoma (laBCC) or metastatic BCC (mBCC), two difficult‐to‐treat populations, have had limited treatment options.
J. Lear, M. Migden, K. Lewis, A. Chang, A. Guminski, R. Gutzmer, L. Dirix, P. Combemale, A. Stratigos, Ruth Plummer, H. Castro, Tingting Yi, M. Mone, Jocelyn Zhou, U. Trefzer, M. Kaatz, Carmen Loquai, R. Kudchadkar, D. Sellami, R. Dummer   +19 more
semanticscholar   +1 more source

Non melanoma skin cancer pathogenesis overview [PDF]

, 2018
(1)Background: Non-melanoma skin cancer is the most frequently diagnosed cancer in humans. The process of skin carcinogenesis is still not fully understood.
Bottoni Ugo, Cantisani Carmen, Didona Dario, Paolino Giovanni   +3 more
core   +1 more source

Chemoprevention of Basal and Squamous Cell Carcinoma With a Single Course of Fluorouracil, 5%, Cream: A Randomized Clinical Trial

JAMA dermatology, 2018
Importance Keratinocyte carcinoma (ie, cutaneous basal and squamous cell carcinoma) is the most common cancer in the United States. Objective To determine whether topical fluorouracil could prevent surgically treated keratinocyte carcinoma.
M. Weinstock, S. Thwin, J. Siegel, K. Marcolivio, A. Means, N. Leader, F. M. Shaw, D. Hogan, D. Eilers, S. Swetter, Suephy C. Chen, S. Jacob, E. Warshaw, G. Stricklin, R. Dellavalle, N. Sidhu-Malik, N. Konnikov, V. Werth, J. Keri, L. Robinson-Bostom, R. Ringer, R. Lew, Ryan E Ferguson, J. DiGiovanna, Grant D. Huang   +24 more
semanticscholar   +1 more source

Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulation

FEBS Letters, EarlyView.
Transcriptional and epigenetic regulation controls autophagy, which exerts context‐dependent effects on cancer: Autophagy suppresses tumorigenesis by maintaining cellular homeostasis or promotes tumor progression by supporting survival under stress. In this “In a Nutshell” article, we explore the intricate mechanisms of the dual function of autophagy ...
Young Suk Yu, Ik Soo Kim, Sung Hee Baek
wiley   +1 more source

Gorlin syndrome in a patient with skin type VI [PDF]

, 2019
Gorlin syndrome, also known as nevoid basal cell carcinoma syndrome, is a rare autosomal dominant disorder that is characterized by multiple basal cell carcinomas developing at a young age, keratocystic odontogenic tumors of the jaw, palmar or plantar ...
Anderson, Kathryn L, Difato, Thomas C, Poladian, Katlin, Taylor, Sarah L   +3 more
core  

Components of cell-matrix linkage as potential new markers for prostate cancer [PDF]

, 2011
Prostate cancer is one of the most common tumor diseases worldwide. Often being non-aggressive, prostate tumors in these cases do not need immediate treatment.
Eble, Johannes Andreas, Navdaev, Alexey
core   +2 more sources