Results 81 to 90 of about 2,712,964 (379)

Two different scenarios of squamous cell carcinoma within advanced Basal cell carcinomas: cases illustrating the importance of serial biopsy during vismodegib usage.

JAMA dermatology, 2014
IMPORTANCE Vismodegib is a Hedgehog signaling pathway inhibitor recently approved by the US Food and Drug Administration for advanced basal cell carcinoma.
G. Zhu, U. Sundram, A. Chang
semanticscholar   +1 more source

ERBIN limits epithelial cell plasticity via suppression of TGF‐β signaling

FEBS Letters, EarlyView.
In breast and lung cancer patients, low ERBIN expression correlates with poor clinical outcomes. Here, we show that ERBIN inhibits TGF‐β‐induced epithelial‐to‐mesenchymal transition in NMuMG breast and A549 lung adenocarcinoma cell lines. ERBIN suppresses TGF‐β/SMAD signaling and reduces TGF‐β‐induced ERK phosphorylation.
Chao Li, Gerard van der Zon, Peter ten Dijke, Tong Shen   +3 more
wiley   +1 more source

Skin cancer by state and territory [PDF]

, 2014
Presents the number of new skin cancer problems managed per 100,000 encounters nationally and for each state and territory, from April 2008 to March 2013.
Allan Pollack, Helena Britt, Joan Henderson, Mark McGrath   +3 more
core  

Periacinar clefting and p63 immunostaining in prostatic intraepithelial neoplasia and prostatic carcinoma [PDF]

, 2006
The aim of the present study was to correlate the presence and extent of retraction clefting and the expression of p63 in neoplastic glands and glands with prostatic intraepithelial neoplasia (PIN) in needle core biopsies.
Belicza, Mladen, Cviko, Aida, Krušlin, Božo, Odak, Ljubica, Tomas, Davor, Čupić, Hrvoje   +5 more
core   +1 more source

Histologic Mimics of Basal Cell Carcinoma.

Archives of Pathology & Laboratory Medicine, 2017
CONTEXT - Basal cell carcinoma (BCC) is the most common human malignant neoplasm and is a frequently encountered diagnosis in dermatopathology. Although BCC may be locally destructive, it rarely metastasizes.
Lauren M. Stanoszek, Grace Y. Wang, P. Harms   +2 more
semanticscholar   +1 more source

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

Molecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka, Tatsuo Nakagawa, Yusuke Ono, Yoshio Kamura, Takeshi Ishida, Hidemasa Kawabata, Kenji Takahashi, Hiroki Sato, Andrew S. Liss, Yusuke Mizukami, Takahide Yokoi   +10 more
wiley   +1 more source

Pilomatrix carcinoma of the lacrimal caruncle: a case report. [PDF]

, 2020
A 45-year-old man presented with a 3-month history of a mass located in the caruncle of his right eye. An incisional biopsy had been performed one month prior by another specialist, and the histopathology report showed basal cell carcinoma.
Acıkalin, Arbil, Ciloglu, Emine, Harbiyeli, Ibrahim Inan, Ozcan, Altan A, Shields, Carol L   +4 more
core   +1 more source

New basal cell carcinoma susceptibility loci. [PDF]

, 2015
To access publisher's full text version of this article, please click on the hyperlink in Additional Links field or click on the hyperlink at the top of the page marked Files.
Benediktsdottir, Kristrun R, Corredera, Cristina, Fuentelsaz, Victoria, Gilaberte, Yolanda, Grasa, Matilde, Gudbjartsson, Daniel F, Gudjonsson, Sigurjon A, Gudmundsson, Julius, Gurzau, Eugene, Halldorsson, Bjarni V, Helgason, Hannes, Johannsdottir, Hrefna, Jonasson, Jon G, Kehr, Birte, Kong, Augustine, Koppova, Kvetoslava, Kristinsdottir, Anna M, Kumar, Rajiv, Magnusson, Olafur T, Masson, Gisli, Mayordomo, José I, Nagore, Eduardo, Nexø, Bjørn A, Olafsson, Jon H, Overvad, Kim, Planelles, Dolores, Rafnar, Thorunn, Ragnarsson, Rafn, Rudnai, Peter, Sanmartin, Onofre, Sigurdsson, Asgeir, Sigurgeirsson, Bardur, Stacey, Simon N, Stefansson, Hreinn, Stefansson, Kari, Sulem, Patrick, Thorisdottir, Kristin, Thorleifsson, Gudmar, Thorsteinsdottir, Unnur, Tjønneland, Anne, Tryggvadottir, Laufey, Vogel, Ulla, Zink, Florian   +42 more
core   +1 more source

Resistance to anti-PD-1-based immunotherapy in basal cell carcinoma: a case report and review of the literature

Journal of Immunotherapy for Cancer, 2018
BackgroundImmunotherapy with immune checkpoint inhibitors has radically changed the management of a broad spectrum of tumors. In contrast, only very limited information is available about the efficacy of these therapies in non-melanoma skin cancers ...
Francesco Sabbatino, A. Marra, Luigi Liguori, G. Scognamiglio, C. Fusciello, G. Botti, S. Ferrone, S. Pepe   +7 more
semanticscholar   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source