Results 71 to 80 of about 27,260,641 (372)

Alterations of striatal indirect pathway neurons precede motor deficits in two mouse models of Huntington's disease

open access: yesNeurobiology of Disease, 2017
Striatal neurons forming the indirect pathway (iSPNs) are particularly vulnerable in Huntington's disease (HD). In this study we set out to investigate morphological and physiological alterations of iSPNs in two mouse models of HD with relatively slow ...
Irene Sebastianutto   +2 more
doaj  

Opponent and bidirectional control of movement velocity in the basal ganglia

open access: yesNature, 2016
For goal-directed behaviour it is critical that we can both select the appropriate action and learn to modify the underlying movements (for example, the pitch of a note or velocity of a reach) to improve outcomes.
E. A. Yttri, J. Dudman
semanticscholar   +1 more source

Neuropeptide Co-Release with Gaba May Explain Functional Non-Monotonic Uncertainty Responses in Dopamine Neurons [PDF]

open access: yes, 2007
Co-release of the inhibitory neurotransmitter GABA and the neuropeptide substance-P (SP) from single axons is a conspicuous feature of the basal ganglia, yet its computational role, if any, has not been resolved.
Bullock, Daniel, Tan, Can Ozan
core   +1 more source

Binary and nonbinary description of hypointensity for search and retrieval of brain MR images [PDF]

open access: yes, 2009
Diagnosis accuracy in the medical field, is mainly affected by either lack of sufficient understanding of some diseases or the inter/intra-observer variability of the diagnoses.
Cetin, Mujdat   +9 more
core   +1 more source

Engineering the Future of Restorative Clinical Peripheral Nerve Surgery

open access: yesAdvanced Healthcare Materials, EarlyView.
What if damaged nerves could regenerate more effectively? This review unveils cutting‐edge strategies to restore nerve function, from biomaterial scaffolds and bioactive molecules to living engineered tissues. By accelerating axonal regrowth, preserving Schwann cells, and enhancing connectivity, these approaches are reshaping nerve repair—offering new ...
Justin C. Burrell   +5 more
wiley   +1 more source

A basal ganglia circuit for evaluating action outcomes

open access: yesNature, 2016
The basal ganglia, a group of subcortical nuclei, play a crucial role in decision-making by selecting actions and evaluating their outcomes. While much is known about the function of the basal ganglia circuitry in selection, how these nuclei contribute ...
Marcus Stephenson-Jones   +9 more
semanticscholar   +1 more source

Role of endogenous cannabinoids in the control of basal ganglia activity [PDF]

open access: yes, 2007
The cannabinoid system is a novel intercellular signaling system that plays a prominent role, among others, in the control of basal ganglia function.
Fernandez-Ruiz, Javier   +3 more
core  

The Case of a 67‐Year‐Old Man With Memory Difficulties and Altered Sleep

open access: yes
Annals of Clinical and Translational Neurology, EarlyView.
Wesley Peng, Borna Bonakdarpour
wiley   +1 more source

Covalent Binding of Dexamethasone to Polyimide Improves Biocompatibility of Neural Implantable Devices

open access: yesAdvanced Healthcare Materials, EarlyView.
The covalent binding of dexamethasone to the surface of polyimide represents the electrically inert part of implantable intraneural devices. This ensures a sustained release of the drug for 9 weeks. In vitro and in vivo tests confirm the reduction of the foreign body reactions and the improved biocompatibility of dexamethasone functionalized polyimide.
Giulia Turrin   +19 more
wiley   +1 more source

Role of the Basal Ganglia in Balance Control

open access: yesNeural Plasticity, 2005
In this review paper, we summarize the important contributions of the basal ganglia to the regulation of postural control. After a brief overview of basal ganglia circuitries, the emphasis is on clinical observations in patients with focal lesions in ...
Jasper E. Visser, Bastiaan R. Bloem
doaj   +1 more source

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