Results 101 to 110 of about 117,087 (348)

Methyl CpG-binding protein 2 participating in the regulation of differentiation plasticity of nerve regeneration in the basal ganglia after ischemic stroke

Chinese Journal of Contemporary Neurology and Neurosurgery, 2013
Background It is accepted that cerebral ischemia induces neurogenesis and neural stem cells (NSCs) differentiation in non-neurogenic regions (especially in the basal ganglia).
Pan LI, Yu-ying ZHOU
doaj  

Neuropsychiatric manifestations of Fahr′s disease pathogenesis and potential for treatment

Industrial Psychiatry Journal, 2013
Fahr′s disease (FD) is a rare neuropsychiatric disease consisting of bilateral basal ganglia calcification with neurological, cognitive, and psychiatric manifestations. We report here a sporadic case of FDs with its neuropsychology.
Raheel Mushtaq, Sheikh Shoib, M. S. V. K Raju, Nilesh Naphade, Tabindah Shah, Alka Pawar   +5 more
doaj   +1 more source

Imaging Studies of Aging, Neurodegenerative Disease, and Alcoholism. [PDF]

, 1995
Neurodegenerative diseases such as Alzheimers disease, disorders such as alcoholism, and the aging process can lead to impaired cognitive function and dementia.
Eberling, Jamie, JAGUST, William J
core  

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende, Emilien Petit, Young Woo Park, Sophie Tezenas du Montcel, James M. Joers, Jonathan M. DuBois, H. Moore Arnold, Michal Povazan, Ipek Özdemir, Guita Banan, Romain Valabregue, Philipp Ehses, Jennifer Faber, Chiadi U. Onyike, Peter B. Barker, Jeremy D. Schmahmann, Eva‐Maria Ratai, Sub H. Subramony, Thomas H. Mareci, Khalaf O. Bushara, Henry Paulson, Thomas Klockgether, Alexandra Durr, Tetsuo Ashizawa, Christophe Lenglet, Gülin Öz, READISCA Investigators   +26 more
wiley   +1 more source

The cardiovascular risk profile of patients with Primary Familial Brain Calcification

Journal of Rare Diseases
Purpose Primary Familial Brain Calcification (PFBC) is a rare neurologic disease characterized by basal ganglia calcifications. Data on cardiovascular risks in this population are limited.
Birgitta M. G. Snijders, Pim A. de Jong, Mike J. L. Peters, Bouke D. W. T. Lith, Eva H. Brilstra, Ynte M. Ruigrok, Vera P. M. Schepers, Evelien van Valen, Marielle H. Emmelot-Vonk, Huiberdina L. Koek   +9 more
doaj   +1 more source

Familial deep cavitating state with a glutathione metabolism defect

Annals of Clinical and Translational Neurology, 2019
Adult genetic disorders causing brain lesions have been mostly described as white matter vanishing diseases. We present here the investigations realized in patients referred for psychiatric disorder with magnetic resonance imaging showing atypical basal ...
John Rendu, Laetitia Van Noolen, Catherine Garrel, Julie Brocard, Isabelle Marty, Christelle Corne, Julien Fauré, Gérard Besson   +7 more
doaj   +1 more source

Neurophysiological Correlates of Gait in the Human Basal Ganglia and the PPN Region in Parkinson’s Disease [PDF]

, 2020
Rene Molina, Chris J. Hass, Kristen Sowalsky, Abigail C. Schmitt, Enrico Opri, Jaime A. Roper, Daniel Martínez-Ramírez, Christopher W. Hess, Kelly D. Foote, Michael S. Okun, Aysegul Gunduz   +10 more
openalex   +1 more source

Brain Areas Associated with Force Steadiness and Intensity During Isometric Ankle Dorsiflexion in Men and Women [PDF]

, 2014
Although maintenance of steady contractions is required for many daily tasks, there is little understanding of brain areas that modulate lower limb force accuracy.
Hunter, Sandra K., Nielson, Kristy A., Vanden Noven, Marnie Lynn, Yoon, Tejin   +3 more
core   +2 more sources

Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher, Charles B. Malpas, Stuart J. McDonald, William T. O’Brien, Craig Despott, Kelly L. Bertram, Matthew P. Pase, Lukas Frontzkowski, Meng Law, Terence J. O’Brien, Lucy Vivash   +10 more
wiley   +1 more source

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett, Abigail Dubois, Melanie Leguizamon, Alexander Song, Paula Trujillo, Colin D. McKnight, Ciaran M. Considine, Manus J. Donahue, Daniel O. Claassen   +8 more
wiley   +1 more source